Linglei Kong
Peking Union Medical College
16 Papers
7 Citations
Linglei Kong is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Medicine & Stroke. The author has an hindex of 4, co-authored 9 publications.
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Papers
The strategies and techniques of drug discovery from natural products.
TL;DR: The bioinformation and artificial intelligence have facilitated the research and development of natural products and led to the new strategies in drug discovery from natural products.
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Pinocembrin Protects Blood-Brain Barrier Function and Expands the Therapeutic Time Window for Tissue-Type Plasminogen Activator Treatment in a Rat Thromboembolic Stroke Model
TL;DR: It is demonstrated that PCB pretreatment shortly before t-PA infusion significantly protects BBB function and improves neurological outcomes following prolonged ischemia beyond the regular 4.5 hr t- PA time window.
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
Cheng-di Liu,Nan-nan Liu,Nan-nan Liu,Sen Zhang,Guodong Ma,Haiguang Yang,Linglei Kong,Guanhua Du +7 more
TL;DR: The results suggest that SAA protects cerebrovascular endothelial cells against ischemia and OGD injury via suppressing Src signaling pathway, and shows that pretreatment with SAA is a potential therapeutic strategy for the prevention of ischemic stroke.
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Differences in the prevention and control of cardiovascular and cerebrovascular diseases.
TL;DR: In this paper, a review of the prevention and control of cardiovascular diseases and cerebrovascular diseases is presented, and the differences in prevention effects and pathological and physiological structures pertaining to CEVDs and CAVDs are analyzed.
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Neutrophil extracellular traps: A novel target for the treatment of stroke.
Ziyuan Zhao,Zirong Pan,Sen Zhang,Guodong Ma,Wen Zhang,Junke Song,Yuehua Wang,Linglei Kong,Guanhua Du +8 more
TL;DR: In this article , the authors provided a reference for the pathogenesis, drug targets, biomarkers and drug development of neutrophil extracellular traps (NETs) in stroke and discussed the potential of NETs as biomarker and the treatment of stroke targeting NETs.
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