Lei Wan
Anhui University
11 Papers
13 Citations
Lei Wan is an academic researcher from Anhui University. The author has contributed to research in topics: Medicine & Superoxide dismutase. The author has an hindex of 4, co-authored 11 publications.
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Papers
RNA-seq reveals the circular RNA and miRNA expression profile of peripheral blood mononuclear cells in patients with rheumatoid arthritis.
Jianting Wen,Jian Liu,Pingheng Zhang,Hui Jiang,Ling Xin,Lei Wan,Yue Sun,Dan Huang,Yanqiu Sun,Yan Long,Ying Zhang,Bingxi Bao,Guanghan Sun +12 more
TL;DR: Exposure to circRNAs specifically expressed in peripheral blood mononuclear cells from rheumatoid arthritis patients may serve as potential biomarkers for the diagnosis of RA, and thesecircRNAs may influence the occurrence and development of RA.
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A Novel Chinese Medicine, Xinfeng Capsule, Modulates Proinflammatory Cytokines via Regulating the Toll-Like Receptor 4 (TLR4)/Mitogen-Activated Protein Kinase (MAPK)/Nuclear Kappa B (NF-κB) Signaling Pathway in an Adjuvant Arthritis Rat Model.
Yunxiang Cao,Dan Huang,Jian Liu,Rui-Kai Zong,Lei Wan,Chuanbing Huang,Wan-Dong Zhang,Yuan Wang +7 more
TL;DR: Xinfeng capsule, a traditional Chinese medicine preparation, protects against cardiac injury in AA rats by modulating proinflammatory cytokines expression via the TLR4/MAPK/NF-κB signaling pathway.
[Huangqin Qingre Chubi Capsules in improving oxidative stress of patients with ankylosing spondylitis via activating PPARγ mediated AMPK/FOXO3a pathway].
TL;DR: HQC can effectively improve the clinical symptoms and oxidative stress of AS patients, and its mechanism may be related to activating PPARγ and up-regulating AMPK/FOXO3a signal pathway.
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Prediction of Self-Perception of Patient in Rheumatoid Arthritis With the Key RNAs Expression Profiles.
Jianting Wen,Jian Liu,Bing Wang,Hui Jiang,Lei Wan,Ling Xin,Yue Sun,Yanqiu Sun,Ying Zhang,Xinlei Du,Xin Wang,Jie Wang +11 more
TL;DR: Quantitative analysis revealed that RA patients with poor self-perception were closely associated with RNAs expression, and 3 key molecules including AC019117.2, LINC00638, and hsa_circ_0003972 could be used to predict self-Perception changes in RA patients.
•Journal Article
[Up-regulated expressions of HIF-1α, VEGF and CD34 promote synovial angiogenesis in rats with adjuvant arthritis].
TL;DR: The synovial angiogenesis is associated with the over-expressions of VEGF, HIF-1α and CD34 in rats with adjuvant arthritis.
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