9 Papers
9 Citations
Lan Wang is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Medicine & Immune system. The author has an hindex of 3, co-authored 6 publications.
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Papers
A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System.
Di Wu,Meng Qin,Duo Xu,Lan Wang,Chaoyong Liu,Jie Ren,George Zhou,Chen Chen,Fengmei Yang,Yanyan Li,Yuan Zhao,Ruyi Huang,Sina Pourtaheri,Chunsheng Kang,Masakazu Kamata,Irvin S. Y. Chen,Zhanlong He,Jing Wen,Wei Chen,Yunfeng Lu +19 more
TL;DR: A CNS delivery platform for protein therapeutics, achieved by encapsulating the proteins within nanocapsules that contain choline and acetylcholine analogues, is reported herein, opening a new avenue for the treatment of CNS diseases.
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Insoluble dietary fibers from Lentinus edodes stipes improve the gel properties of pork myofibrillar protein: A water distribution, microstructure and intermolecular interactions study.
TL;DR: In this article , the authors investigated the effects of Lentinus edodes stipes insoluble dietary fiber (LESIDF, 0%-3.0%) on the quality and microscopic properties of pork myofibrillar protein (MP) gels.
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Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
Jing Wen,Tracy Cheever,Lan Wang,Di Wu,Jason S. Reed,John R. Mascola,Xuejun Chen,Cuiping Liu,Amarendra Pegu,Jonah B. Sacha,Jonah B. Sacha,Yunfeng Lu,Nancy L. Haigwood,Irvin S. Y. Chen +13 more
TL;DR: In this article, a single dose of PGT121 encased in nanocapsules when delivered at 48h post-infection delays early acute infection with SHIVSF162P3 in infants, with one of four animals demonstrating viral clearance.
Efficacy of Antibodies Targeting TfR1 in Xenograft Mouse Models of AIDS-Related Non-Hodgkin Lymphoma
Tracy R. Daniels-Wells,Pierre V. Candelaria,Emiko Kranz,Jing Wen,Lan Wang,Masakazu Kamata,Juan Carlos Almagro,Otoniel Martinez-Maza,Manuel L. Penichet +8 more
TL;DR: In this article , transferrin receptor 1 (TfR1) was shown to be a meaningful target for antibody-based anti-Hodgkin lymphoma (NHL) therapy.
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Nanoencapsulated rituximab mediates superior cellular immunity against metastatic B-cell lymphoma in a complement competent humanized mouse model
Jing Wen,Lan Wang,Jie Ren,Emiko Kranz,Shilin Chen,Di Wu,Toshio Kanazawa,Irvin S. Y. Chen,Yunfeng Lu,Masakazu Kamata +9 more
TL;DR: In this paper, the authors developed a humanized mouse model using a novel NSG strain, NOD.Cg−Hc1Prkdcscid Il2rgtm1Wjl/SzJ (NSG−HC1), which contains the corrected mutation in the Hc gene to support CDC in addition to other mechanisms endowed by humanization, and evaluated the anticancer efficacies of nanoencapsulated rituximab after xenograft of the human Burkitt lymphoma cell line 2F7-BR44.
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