Kurt Einarsson
Karolinska Institutet
201 Papers
3.7K Citations
Kurt Einarsson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Cholesterol & Bile acid. The author has an hindex of 51, co-authored 201 publications. Previous affiliations of Kurt Einarsson include University of California, San Diego & University of Oslo.
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Papers
Influence of age on secretion of cholesterol and synthesis of bile acids by the liver.
TL;DR: Cholesterol saturation of bile increases with age as a consequence of enhanced hepatic secretion of cholesterol and decreased bile acid synthesis, which may explain why age is a risk factor for the development of cholesterol gallstones.
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Effect of Biliary Drainage on Individual Reactions in the Conversion of Cholesterol to Taurocholic Acid
TL;DR: It is suggested that the hydroxylation of cholesterol to cholest-5-ene-3β, 7α-diol might be a rate-determining step in the conversion ofolesterol to bile acids.
258
Neonatal Imprinting of Liver Microsomal Hydroxylation and Reduction of Steroids
TL;DR: The microsomal steroid-metabolizing enzyme activities may be grouped into three classes with regard to the mechanisms regulating their activity: (a) enzymes with a basal activity level regulated by nongonadal factors but reversibly inducible by androgens; (b) enzymes irreversibly "imprinted" or "programmed" by andosterone during the prepubertal period and reversibly stimulated by androgens postpubertally.
234
Influence of age on the metabolism of plasma low density lipoproteins in healthy males.
TL;DR: It is concluded that the increase in LDL which normally occurs with age is explained by a reduced capacity for its removal, and hypothesize that this is mediated via a reduced hepatic LDL receptor expression.
Effects of interruption of the enterohepatic circulation of bile acids on the transport of very low density-lipoprotein triglycerides
Ulrich Beil,Ulrich Beil,John R. Crouse,John R. Crouse,Kurt Einarsson,Kurt Einarsson,Scott M. Grundy,Scott M. Grundy +7 more
TL;DR: Data show that when treatment with bile acid sequestrants causes an increase in plasma VLDL-TG, the increase is due to an increment in production and not to a decrease in catabolism.
132