Kouichi Kitamura
National Institutes of Health
43 Papers
355 Citations
Kouichi Kitamura is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Hepatitis B virus & Activation-induced (cytidine) deaminase. The author has an hindex of 21, co-authored 43 publications. Previous affiliations of Kouichi Kitamura include Osaka University & Kyoto University.
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Papers
Mice deficient in the axonemal protein Tektin-t exhibit male infertility and immotile-cilium syndrome due to impaired inner arm dynein function.
Hiromitsu Tanaka,Naoko Iguchi,Yoshiro Toyama,Kouichi Kitamura,Tohru Takahashi,Kazuhiro Kaseda,Mamiko Maekawa,Yoshitake Nishimune +7 more
TL;DR: The tektin-t gene is one of the causal genes for immotile-cilium syndrome/primary ciliary dyskinesia and that the loss of Tektin-t results in impaired motility of both flagella and cilia.
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Interleukin-1 and Tumor Necrosis Factor-α Trigger Restriction of Hepatitis B Virus Infection via a Cytidine Deaminase Activation-induced Cytidine Deaminase (AID)
Koichi Watashi,Guoxin Liang,Masashi Iwamoto,Hiroyuki Marusawa,Nanako Uchida,Takuji Daito,Kouichi Kitamura,Masamichi Muramatsu,Hirofumi Ohashi,Tomoko Kiyohara,Ryosuke Suzuki,Jisu Li,Shuping Tong,Yasuhito Tanaka,Kazumoto Murata,Hideki Aizaki,Takaji Wakita +16 more
TL;DR: It is found that pretreatment with IL-1β and TNFα remarkably reduced the host cell susceptibility to HBV infection, and this effect was mediated by activation of the NF-κB signaling pathway.
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Efficient detection of SARS-CoV-2 RNA in the solid fraction of wastewater.
TL;DR: Results demonstrate that viral recovery from the solid fraction is an effective method for SARS-CoV-2 RNA surveillance in an aqueous environment.
156
HANP1/H1T2, a Novel Histone H1-Like Protein Involved in Nuclear Formation and Sperm Fertility
Hiromitsu Tanaka,Naoko Iguchi,Ayako Isotani,Kouichi Kitamura,Yoshiro Toyama,Yasuhiro Matsuoka,Masayoshi Onishi,Kumiko Masai,Mamiko Maekawa,Kiyotaka Toshimori,Masaru Okabe,Yoshitake Nishimune +11 more
TL;DR: It is found that HANP1/H1T2 is essential for nuclear formation in functional spermatozoa and is specifically involved in the replacement of histones with protamines during spermiogenesis.
133
Refined x-ray structure of papain.E-64-c complex at 2.1-A resolution.
D. Yamamoto,K. Matsumoto,Hirofumi Ohishi,Toshimasa Ishida,Masao Inoue,Kouichi Kitamura,Hiroki Mizuno +6 more
TL;DR: In the complex structure, the configurational conversion from S to R took place on the epoxy carbon of E-64-c, implying that the nucleophilic attack of the Cys-25 thiol group occurs at the opposite side of the Epoxy oxygen atom.
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