Kevin K. Zhou
University of Oklahoma Health Sciences Center
12 Papers
1 Citations
Kevin K. Zhou is an academic researcher from University of Oklahoma Health Sciences Center. The author has contributed to research in topics: Wnt signaling pathway & LRP6. The author has an hindex of 10, co-authored 11 publications. Previous affiliations of Kevin K. Zhou include Hamm AG & University of Oklahoma.
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Papers
MicroRNA-200b downregulates oxidation resistance 1 (Oxr1) expression in the retina of type 1 diabetes model.
Anne R. Murray,Qian Chen,Yusuke Takahashi,Yusuke Takahashi,Kevin K. Zhou,Kyoungmin Park,Kyoungmin Park,Jian Xing Ma +7 more
TL;DR: It is suggested that miR-200b-regulated Oxr1 potentially has a protective role in diabetic retinopathy.
105
The pathogenic role of the canonical Wnt pathway in age-related macular degeneration.
TL;DR: Activation of the canonical Wnt pathway is sufficient to induce retinal inflammation and oxidative stress and plays a pathogenic role in age-related macular degeneration and diabetic retinopathy.
99
Inhibition of Connective Tissue Growth Factor Overexpression in Diabetic Retinopathy by SERPINA3K via Blocking the WNT/β-Catenin Pathway
TL;DR: Serine proteinase inhibitor SERPINA3K is an antifibrogenic factor, and its antifIBrogenic activity is through blocking the Wnt pathway.
86
Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family.
TL;DR: The blockade of Wnt signaling may represent a unifying mechanism for the anti-inflammatory and anti-angiogenic effects of SERPINA3K.
85
Impacts of hypoxia-inducible factor-1 knockout in the retinal pigment epithelium on choroidal neovascularization.
Mingkai Lin,Yang Hu,Ying Chen,Kevin K. Zhou,Ji Jin,Meili Zhu,Yun-Zheng Le,Jian Ge,Jian Xing Ma +8 more
TL;DR: RPE-derived HIF-1α plays a key role in CNV, but not in ischemia-induced retinal NV, as shown by light microscopy and electroretinogram recording.