Kai Friedrichs
Ruhr University Bochum
71 Papers
83 Citations
Kai Friedrichs is an academic researcher from Ruhr University Bochum. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 17, co-authored 30 publications. Previous affiliations of Kai Friedrichs include University of Hamburg & University of Cologne.
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Papers
Transcatheter Treatment of Severe Tricuspid Regurgitation With the Edge-to-Edge MitraClip Technique
Georg Nickenig,Marek Kowalski,Jörg Hausleiter,Daniel Braun,Joachim Schofer,Ermela Yzeiraj,Volker Rudolph,Kai Friedrichs,Francesco Maisano,Maurizio Taramasso,Neil Fam,Giovanni Bianchi,Francesco Bedogni,Paolo Denti,Ottavio Alfieri,Azeem Latib,Antonio Colombo,Christoph Hammerstingl,Robert Schueler +18 more
TL;DR: Initial efficacy analysis showed encouraging reduction of TR, which may potentially result in improved clinical outcomes, and transcatheter treatment of TR with the MitraClip system seems to be safe and feasible in this cohort of preselected patients.
351
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Volker Rudolph,René Andrié,Tanja K. Rudolph,Kai Friedrichs,Anna Klinke,Birgit Hirsch-Hoffmann,Alexander P. Schwoerer,Denise Lau,Xiaoming Fu,Karin Klingel,Karsten Sydow,Michael Didié,Michael Didié,Anika Seniuk,Eike Christin Von Leitner,Katalin Szoecs,Jan W. Schrickel,Hendrik Treede,Ulrich Wenzel,Thorsten Lewalter,Georg Nickenig,Wolfram-Hubertus Zimmermann,Wolfram-Hubertus Zimmermann,Thomas Meinertz,Rainer H. Böger,Hermann Reichenspurner,Bruce A. Freeman,Thomas Eschenhagen,Heimo Ehmke,Stanley L. Hazen,Stephan Willems,Stephan Baldus +31 more
TL;DR: Experimental and clinical evidence for the mechanistic involvement of myeloperoxidase (MPO), a heme enzyme abundantly expressed by neutrophils, in the pathophysiology of atrial fibrillation is provided.
347
6-Month Outcomes of Tricuspid Valve Reconstruction for Patients With Severe Tricuspid Regurgitation.
Georg Nickenig,Marcel Weber,Robert Schueler,Jörg Hausleiter,Michael Nabauer,Ralph Stephan von Bardeleben,Efthymios Sotiriou,Ulrich Schäfer,Florian Deuschl,Karl-Heinz Kuck,Felix Kreidel,Jean Michel Juliard,Eric Brochet,Azeem Latib,Eustachio Agricola,Stephan Baldus,Kai Friedrichs,Prashanthi Vandrangi,Patrick Verta,Rebecca T. Hahn,Francesco Maisano +20 more
TL;DR: Six-month outcomes show that the transcatheter tricuspid valve reconstruction system performs as intended and appears to be safe in patients with symptomatic and moderate to severe functional TR.
211
Predictors of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement With the SAPIEN 3.
Victor Mauri,Andreas Reimann,Daniel Stern,Maximilian Scherner,Elmar W. Kuhn,Volker Rudolph,Stephan Rosenkranz,Kaveh Eghbalzadeh,Kai Friedrichs,Thorsten Wahlers,Stephan Baldus,Navid Madershahian,Tanja K. Rudolph +12 more
TL;DR: LVOTLC and LVOTRC calcium load, baseline right bundle branch block, and implantation depth were identified as independent predictors of the need for PPMI post-TAVR, and patient groups with different P PMI risk could be stratified using these 4 predictors.
200
Myeloperoxidase attracts neutrophils by physical forces
Anna Klinke,Claudia Nussbaum,Lukáš Kubala,Kai Friedrichs,Tanja K. Rudolph,Volker Rudolph,Hans-Joachim Paust,Christine Schröder,Daniel Benten,Denise Lau,Katalin Szöcs,Paul G. Furtmüller,Peter Heeringa,Karsten Sydow,Hans-Jürgen Duchstein,Heimo Ehmke,Udo Schumacher,Thomas Meinertz,Markus Sperandio,Stephan Baldus +19 more
TL;DR: Evidence is provided for myeloperoxidase (MPO), an abundant PMN-derived heme protein, facilitating PMN recruitment by its positive surface charge, which highlights a principal mechanism of PMN attraction driven by physical forces.
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