Julian Eschenbruch
Forschungszentrum Jülich
7 Papers
21 Citations
Julian Eschenbruch is an academic researcher from Forschungszentrum Jülich. The author has contributed to research in topics: Focal adhesion & Tumor suppressor gene. The author has an hindex of 4, co-authored 7 publications. Previous affiliations of Julian Eschenbruch include RWTH Aachen University.
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Papers
Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR
Vera Kloten,Nadine Rüchel,Nadina Ortiz Brüchle,Janina Gasthaus,Nils Freudenmacher,Florian Steib,Jolein Mijnes,Julian Eschenbruch,Marcel Binnebösel,Ruth Knüchel,Edgar Dahl +10 more
TL;DR: Total cfDNA was significantly increased in cancer patients compared to healthy controls, with the highest yield in patients with distant metastatic disease, and choice of pre-analytical extraction systems needs to be more carefully validated in routine clinical practice.
Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients.
Martin Schlensog,Lara Magnus,Timon Heide,Julian Eschenbruch,Florian Steib,Maximilian Tator,Vera Kloten,Michael Rose,Erik Noetzel,Nadine T. Gaisa,Ruth Knüchel,Edgar Dahl +11 more
TL;DR: The results indicate that SFRP3 acts as a novel putative tumor suppressor gene in adenocarcinoma of the lung possibly regulating canonical WNT signaling.
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The ECM Modulator ITIH5 Affects Cell Adhesion, Motility and Chemotherapeutic Response of Basal/Squamous-Like (BASQ) Bladder Cancer Cells.
Michael Rose,Erik Noetzel,Jennifer Kistermann,Julian Eschenbruch,Sandra Rushrush,Lin Gan,Ruth Knüchel,Nadine T. Gaisa,Edgar Dahl +8 more
TL;DR: In this paper, the role of ITIH5 in basal-type bladder cancers (BLCA) has been investigated by sub-classifying TCGA BLCA data, and the predominant loss of ITH5 expression in the basal/squamous-like (BASQ) subtype was revealed.
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Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients’ Outcome in Basal-Like Breast Cancer
Vera Kloten,Martin Schlensog,Julian Eschenbruch,Janina Gasthaus,Janina Tiedemann,Jolein Mijnes,Timon Heide,Till Braunschweig,Ruth Knüchel,Edgar Dahl +9 more
TL;DR: The data indicate that the described putative tumor suppressive function of NDRG2 may be confined to luminal- and basal B-type breast cancers.
Cell Force-Driven Basement Membrane Disruption Fuels EGF- and Stiffness-Induced Invasive Cell Dissemination from Benign Breast Gland Acini
Aljona Gaiko-Shcherbak,Julian Eschenbruch,Nils M. Kronenberg,Michael Teske,Benjamin Wolters,Ronald Springer,Malte C. Gather,Malte C. Gather,Rudolf Merkel,Bernd Hoffmann,Erik Noetzel +10 more
TL;DR: In this article, the authors studied the mechanical response of MCF10A-derived human breast cell acini with BMs of tuneable maturation to physical and soluble tumour-like extracellular matrix (ECM) cues.
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