Josef Rueschoff
University of Regensburg
12 Papers
21 Citations
Josef Rueschoff is an academic researcher from University of Regensburg. The author has contributed to research in topics: Cancer & Microsatellite instability. The author has an hindex of 6, co-authored 11 publications.
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Papers
Genotype-Phenotype Comparison of German MLH1 and MSH2 Mutation Carriers Clinically Affected With Lynch Syndrome: A Report by the German HNPCC Consortium
Timm O. Goecke,Karsten Schulmann,Christoph Engel,Elke Holinski-Feder,Constanze Pagenstecher,Hans K. Schackert,Matthias Kloor,Erdmute Kunstmann,Holger Vogelsang,Gisela Keller,Wolfgang Dietmaier,Elisabeth Mangold,Nicolaus Friedrichs,Peter Propping,Stefan Krüger,Johannes Gebert,Wolff Schmiegel,Josef Rueschoff,Markus Loeffler,Gabriela Moeslein +19 more
TL;DR: The proportion ofrectal cancers and shorter time span to metachronous cancers indicates the need for a defined treatment strategy for primary rectal cancers in hereditary nonpolyposis colorectal cancer patients.
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Optimized PD-L1 scoring of gastric cancer
Birgid Schoemig-Markiefka,Jana Eschbach,Andreas H. Scheel,Aylin Pamuk,Josef Rueschoff,Thomas Zander,Reinhard Buettner,Wolfgang Schroeder,Christiane Bruns,Heike Loeser,Hakan Alakus,Alexander Quaas +11 more
TL;DR: In this paper, a comprehensive study to optimize PD-L1 assessment in gastric cancer using endoscopically available tissue was conducted, which showed that using fewer surface biopsies decreased sensitivity and specificity and caused false negative classifications.
Sex-specific prognostic effect of CD66b-positive tumor-infiltrating neutrophils (TANs) in gastric and esophageal adenocarcinoma.
Alexander Quaas,Aylin Pamuk,Sebastian Klein,Jennifer Quantius,Jan Rehkaemper,Atakan Görkem Barutcu,Josef Rueschoff,Thomas Zander,Florian Gebauer,Axel M. Hillmer,Reinhard Buettner,Wolfgang Schroeder,Christiane Bruns,Heike Löser,Birgid Schoemig-Markiefka,Hakan Alakus +15 more
TL;DR: In this article, the authors evaluated the prognostic relevance of tumor-associated neutrophils (TANs) in different molecular subtypes of gastric and esophageal adenocarcinoma.
Occurrence of High Microsatellite-Instability/Mismatch Repair Deficiency in Nearly 2,000 Human Adenocarcinomas of the Gastrointestinal Tract, Pancreas, and Bile Ducts: A Study From a Large German Comprehensive Cancer Center.
Alexander Quaas,Jan Rehkaemper,Josef Rueschoff,Aylin Pamuk,Thomas Zander,Axel M. Hillmer,Janna Siemanowski,Jana Wittig,Reinhard Buettner,Patrick Sven Plum,Felix C. Popp,Florian Gebauer,Christiane Bruns,Heike Loeser,Hakan Alakus,Birgid Schoemig-Markiefka +15 more
TL;DR: In this paper, a large cohort of tumors of the upper gastrointestinal tract was analyzed for microsatellite-instability (MSI-H)/mismatch repair deficiency (MMRd) status, including 1,267 carcinomas of the esophagus or stomach.
Proliferating cell nuclear antigen in normal urothelium and urothelial lesions of the urinary bladder: a quantitative assessment using a true color image analysis system.
TL;DR: The results indicate that PCNA staining using the PC10 antibody is not confined to the proliferative fraction of neoplastic urothelium, and the amount of PCNA is regulated differently in Urothelial neoplasms, emphasizing the biological differences between the following two sets: mild dysplasia and moderate Dysplasia; mild dysPlasia and papillary carcinomas.
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