Ji-Chun Yang
Laboratory of Molecular Biology
6 Papers
45 Citations
Ji-Chun Yang is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Protein structure & Protein subunit. The author has an hindex of 6, co-authored 6 publications.
Chat about Author
Papers
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p
David J. Owen,Prisca Ornaghi,Ji-Chun Yang,Nicholas Lowe,Philip R. Evans,Paola Ballario,David Neuhaus,Patrizia Filetici,Andrew Travers +8 more
TL;DR: The findings suggest that the Gcn5p bromodomain may discriminate between different acetylated lysine residues depending on the context in which they are displayed.
Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2.
Richard P. Grant,Neil J. Marshall,Ji-Chun Yang,Milo B. Fasken,Seth M. Kelly,Michelle T. Harreman,David Neuhaus,Anita H. Corbett,Murray Stewart +8 more
TL;DR: The Nab2 N-terminal domain appears to mediate protein:protein interactions that facilitate the nuclear export of mRNA, and has a distinctive hydrophobic patch centered on Phe73, consistent with this region of the surface being a protein: protein interaction site.
51
How the N-terminal Domain of the OSCP Subunit of Bovine F1Fo-ATP Synthase Interacts with the N-terminal Region of an Alpha Subunit
Rodrigo J. Carbajo,Fiona A. Kellas,Ji-Chun Yang,Michael J. Runswick,Martin G. Montgomery,John E. Walker,David Neuhaus +6 more
TL;DR: An NMR characterisation of the interaction between OSCP-NT and a peptide corresponding to residues 1-25 of the alpha-subunit of bovine F(1)-ATPase is presented.
32
Structural basis of the interaction between P-element somatic inhibitor and U1-70k essential for the alternative splicing of P-element transposase.
TL;DR: The AB box-binding site of U1-70k is mapped to a short proline-rich sequence at the C terminus, which forms an anti-parallel helical hairpin in which four highly conserved aromatic residues form a cluster on one face of the first helix.
20
Identification of new differentiation inducing factors from Dictyostelium discoideum.
Tamao Saito,Graham W. Taylor,Ji-Chun Yang,David Neuhaus,Dmitry A. Stetsenko,Atsushi Kato,Robert R. Kay +6 more
TL;DR: Synthetic MPBD induced morphological stalk cell differentiation and stimulated spore cell differentiation in Dictyostelium discoideum amoebae and was a novel factor and was identified as 4-methyl-5-pentylbenzene-1,3-diol (MPBD) with the structure confirmed by chemical synthesis.