Jane Skjøth-Rasmussen
Copenhagen University Hospital
51 Papers
75 Citations
Jane Skjøth-Rasmussen is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 31 publications.
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Papers
VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance.
Signe Regner Michaelsen,Mikkel Staberg,Henriette Pedersen,Kamilla E. Jensen,Wiktor Majewski,Helle Broholm,Mette K. Nedergaard,Christopher Meulengracht,Thomas Urup,Mette Villingshøj,Slavka Lukacova,Jane Skjøth-Rasmussen,Jannick Brennum,Andreas Kjaer,Ulrik Lassen,Marie-Thérése Stockhausen,Hans Skovgaard Poulsen,Petra Hamerlik +17 more
TL;DR: VEGF-C serves as both a paracrine and an autocrine pro-survival cytokine in glioblastoma, promoting tumor cell survival and tumorigenesis, where its inhibition appears superior to bevacizumab therapy in improving tumor control.
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B
Mikkel Staberg,Rikke Darling Rasmussen,Signe Regner Michaelsen,Henriette Pedersen,Kamilla E. Jensen,Mette Villingshøj,Jane Skjøth-Rasmussen,Jannick Brennum,Kristoffer Vitting-Seerup,Hans Skovgaard Poulsen,Petra Hamerlik +10 more
TL;DR: It is found that the chromatin regulator, JmjC domain histone H3K36me2/me1 demethylase KDM2B, is highly expressed in glioblastoma surgical specimens compared to normal brain, and inhibition causing loss of GSC survival, genomic stability, and chemoresistance.
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Early Postoperative 18F-FET PET/MRI for Pediatric Brain and Spinal Cord Tumors.
Lisbeth Marner,Karsten Nysom,Astrid Sehested,Lise Borgwardt,René Mathiasen,Otto M. Henriksen,Michael Lundemann,Per Munck af Rosenschöld,Carsten Thomsen,Lars Bøgeskov,Jane Skjøth-Rasmussen,Marianne Juhler,Anders Kruse,Helle Broholm,David Scheie,Torsten Lauritsen,Julie Lyng Forman,Peder Skov Wehner,Liselotte Højgaard,Ian Law +19 more
TL;DR: The high specificity for detecting residual tumor suggests that supplementary 18F-FET PET is relevant in cases where reoperation for residual tumor is considered, and this is to the authors' knowledge the first larger study using PET/MRI in pediatric neurooncology.
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Cell-free DNA in newly diagnosed patients with glioblastoma - a clinical prospective feasibility study.
Dorte Schou Nørøxe,Olga Østrup,Christina Westmose Yde,Lise Barlebo Ahlborn,Finn Cilius Nielsen,Signe Regner Michaelsen,Vibeke Andrée Larsen,Jane Skjøth-Rasmussen,Jannick Brennum,Petra Hamerlik,Hans Skovgaard Poulsen,Ulrik Lassen +11 more
TL;DR: There was a good tendency between cfDNA and treatment course and -response, respectively with the highest levels at progression.
Effects of Prostacyclin on Cerebral Blood Flow and Vasospasm After Subarachnoid Hemorrhage: Randomized, Pilot Trial.
Rune Rasmussen,Jørn Wetterslev,Trine Stavngaard,Marianne Juhler,Jane Skjøth-Rasmussen,Per-Olof Grände,Niels Vidiendal Olsen +6 more
TL;DR: Global cerebral blood flow after subarachnoid hemorrhage is not markedly affected by administration of prostacyclin in the tested dose range, and administration of prostatectomyclin to patients with subaraches may be safe and feasible.
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