Jane McGrath

TL;DR: In one of four primary association analyses, the association signal for marker rs4141463, located within MACROD2, crossed the genome-wide association significance threshold of P < 5 × 10−8 and, consistent with the winner's curse, its effect size in the replication sample was much smaller.

TL;DR: Findings suggest an interplay in the abnormal development of the striatal, frontal, and temporal regions in ASD across the lifespan, using a well-established, validated, publicly available analysis pipeline.

TL;DR: Altered lateralized neurodevelopment may be a feature of ASD, affecting widespread brain regions with diverse functions, and particularly in medial frontal, orbitofrontal, cingulate and inferior temporal areas.

TL;DR: Structural brain imaging data from ENIGMA consortium data suggests robust but subtle differences across different age groups among ADHD, ASD, and OCD, which support previous work emphasizing structural brain differences in these disorders.