James R. Moeller

TL;DR: The findings demonstrate that abnormal topographic covariance profiles exist in parkinsonism and have potential clinical application as neuroimaging markers inParkinsonism.

TL;DR: For the old subjects this topography may represent an altered, compensatory network that is used to maintain function in the face of age-related physiological changes, and may represent a neural manifestation of innate or acquired reserve.

TL;DR: The scale subprofile model identified the topographic abnormality as being due to flow reduction in the depressed patients in selective frontal, central, superior temporal, and anterior parietal regions, which may reflect dysfunction in the parallel distributed cortical network involving frontal and temporoparietal polymodal association areas.

TL;DR: In this paper, the authors evaluated the clinical course and predictors of outcome in outpatients with cognitive impairment who do not meet criteria for dementia at initial evaluation and found that low scores on the mMMS delayed recall subtest, consistent long-term retrieval on the Selective Reminding Test, category naming for animals, and the WAIS-R digit symbol, picture arrangement, and block design subtests were predictive of the final diagnosis of dementia.