James E. Lowe
Duke University
177 Papers
2.7K Citations
James E. Lowe is an academic researcher from Duke University. The author has contributed to research in topics: Medicine & Coronary artery disease. The author has an hindex of 49, co-authored 177 publications. Previous affiliations of James E. Lowe include Cornell University & American Heart Association.
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Papers
Adenosine myocardial protection: preliminary results of a phase II clinical trial.
Robert M. Mentzer,Vladimir Birjiniuk,Shukri F. Khuri,James E. Lowe,Peter S. Rahko,Richard D. Weisel,Harry A. Wellons,Matthew Barker,Robert D. Lasley +8 more
TL;DR: Patients who received high- doses of adenosine were less likely to experience one of five adverse events: high-dose dopamine use, epinephrine use, insertion of intraaortic balloon pump, myocardial infarction, or death.
103
Improvement in Inducible Ischemia During Dobutamine Stress Echocardiography After Transmyocardial Laser Revascularization in Patients With Refractory Angina Pectoris
Carolyn L Donovan,Kevin P. Landolfo,James E. Lowe,Fiona M. Clements,Robin B. Coleman,Thomas J. Ryan +5 more
TL;DR: TMLR performed in patients with refractory angina pectoris reduces ischemic wall motion abnormalities and improves stress-induced tolerance during dobutamine echocardiography up to 6 months postoperatively.
103
Acute isovolemic hemodilution and blood transfusion. Effects on regional function and metabolism in myocardium with compromised coronary blood flow
Donat R. Spahn,L. R. Smith,C. D. Veronee,R. L. Mcrae,Wei-Chih Hu,A. J. Menius,James E. Lowe,Bruce J. Leone +7 more
TL;DR: Moderate isovolemic hemodilution is relatively well tolerated in left ventricular myocardium with compromised coronary blood flow, and he modilution regional contractile dysfunction induced by hemodILution is reversible by minimal blood transfusion.
93
Left ventricular dysfunction and dilatation resulting from chronic supraventricular tachycardia.
TL;DR: Long-term supraventricular tachycardia resulted in significant functional changes associated with cardiac enlargement, which were not immediately reversible.
90
Neovascularization after transmyocardial laser revascularization in a model of chronic ischemia
G. Chad Hughes,James E. Lowe,Alan P. Kypson,James D. St. Louis,Anne M. Pippen,Kevin G. Peters,R. Edward Coleman,Timothy R. DeGrado,Carolyn L Donovan,Brian H. Annex,Kevin P. Landolfo +10 more
TL;DR: Evidence is provided that neovascularization is present long term in regions of ischemic, viable myocardium after TMR, suggesting angiogenesis may represent the mechanism of clinical improvement after transmyocardial laser revascularization.
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