J. Marc Pipas
Dartmouth–Hitchcock Medical Center
47 Papers
292 Citations
J. Marc Pipas is an academic researcher from Dartmouth–Hitchcock Medical Center. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 20, co-authored 47 publications. Previous affiliations of J. Marc Pipas include University of Miami & University of Rochester.
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Papers
A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer.
Robert S. Sandler,Susan Halabi,John A. Baron,Susan Budinger,Electra D. Paskett,Roger Keresztes,Nicholas J. Petrelli,J. Marc Pipas,Daniel D. Karp,Charles L. Loprinzi,Gideon Steinbach,Richard L. Schilsky +11 more
TL;DR: In this paper, the authors conducted a randomized, double-blind trial to determine the effect of aspirin on the incidence of colorectal adenomas, which was terminated early by an independent data and safety monitoring board when statistically significant results were reported during a planned interim analysis.
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Analysis of MicroRNAs in Pancreatic Fine-Needle Aspirates Can Classify Benign and Malignant Tissues
Anna E. Szafranska,Martina Doleshal,Hayward S. Edmunds,Stuart R. Gordon,Jutta Lüttges,Johanna Munding,Richard J. Barth,Edward J. Gutmann,Arief A. Suriawinata,J. Marc Pipas,Andrea Tannapfel,Murray Korc,Stephan A. Hahn,Emmanuel Labourier,Gregory J. Tsongalis +14 more
TL;DR: This study is the first to evaluate the diagnostic potential of miRNAs in a clinical setting and has shown that miRNA analysis of pancreatic FNA biopsy samples can aid in the pathologic evaluation of suspicious cases and may provide a new strategy for improving the diagnosis of Pancic diseases.
Pancreatic cyst prevalence and the risk of mucin-producing adenocarcinoma in US adults.
Timothy B. Gardner,Lisa M. Glass,Kerrington D. Smith,Gregory H. Ripple,Richard J. Barth,David A. Klibansky,Thomas A. Colacchio,Michael J. Tsapakos,Arief A. Suriawinata,Gregory J. Tsongalis,J. Marc Pipas,Stuart R. Gordon +11 more
TL;DR: Malignant transformation of pancreatic cysts into mucin-producing adenocarcinoma in US adults is a very rare event and current clinical guidelines and resource allocation for pancreatic Cyst disease should be reconsidered.
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Phase I study of twice-weekly gemcitabine and concomitant external-beam radiotherapy in patients with adenocarcinoma of the pancreas
J. Marc Pipas,Sandra E. Mitchell,Richard J. Barth,Raul Vera-Gimon,Joerg Rathmann,Louise P. Meyer,Richard S Wagman,Lionel D. Lewis,Carol E. McDonnell,Thomas A. Colacchio,Raymond P. Perez +10 more
TL;DR: The data suggest a higher maximum tolerated dose and different dose-limiting toxicity than previously reported, and the combination of external-beam radiation and twice-weekly gemcitabine at a dose of 50 mg/m(2) is well tolerated and shows promising activity for the treatment of pancreatic cancer.
88
Documenting the Natural History of Patients With Resected Stage II Adenocarcinoma of the Colon After Random Assignment to Adjuvant Treatment With Edrecolomab or Observation: Results From CALGB 9581
Donna Niedzwiecki,Monica M. Bertagnolli,Robert S. Warren,Carolyn C. Compton,Nancy E. Kemeny,Al B. Benson,S. Gail Eckhardt,Steven R. Alberts,Gity N. Porjosh,David J. Kerr,Anthony,Philippe Rougier,J. Marc Pipas,Joel H. Schwartz,James M Atkins,Mark Allen O'Rourke,Michael C. Perry,Richard M. Goldberg,Robert J. Mayer,Thomas A. Colacchio +19 more
TL;DR: This large study with a long duration of follow-up provided unique data concerning the natural history of resected stage II colon cancer and no combined prognostic factor model was found to adequately classify patients at higher risk of recurrence or death as a result of colon cancer.