J. Legrand
university of lille
11 Papers
10 Citations
J. Legrand is an academic researcher from university of lille. The author has contributed to research in topics: Gout & Calcium pyrophosphate. The author has an hindex of 5, co-authored 7 publications.
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Papers
Dual-energy computed tomography in calcium pyrophosphate deposition: initial clinical experience
TL;DR: This proof-of-concept study shows that DECT has the potential to discriminate meniscal CPP deposits from calcium HA in subchondral and trabecular bone in vivo, paving the way for the non-invasive biochemical signature assessment of intra- and juxta-articular calcium crystal deposits.
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Monosodium urate burden assessed with dual-energy computed tomography predicts the risk of flares in gout: a 12-month observational study
Tristan Pascart,Agathe Grandjean,Benoist Capon,J. Legrand,Nasser Namane,Vincent Ducoulombier,Marguerite Motte,Marie Vandecandelaere,Hélène Luraschi,Catherine Godart,Eric Houvenagel,Laurène Norberciak,Jean-François Budzik +12 more
TL;DR: This is the first study showing that the extent of monosodium urate (MSU) burden measured with DECT but not US is predictive of the risk of flares.
Association of Specific Comorbidities with Monosodium Urate Crystal Deposition in Urate-Lowering Therapy-Naive Gout Patients: A Cross-Sectional Dual-Energy Computed Tomography Study.
Tristan Pascart,André Ramon,Sébastien Ottaviani,J. Legrand,Vincent Ducoulombier,Eric Houvenagel,Laurène Norberciak,Pascal Richette,Fabio Becce,Paul Ornetti,Jean-François Budzik +10 more
TL;DR: Specific comorbidities, particularly chronic heart failure and diabetes mellitus, are more strongly associated with increased MSU crystal deposition in knees and feet/ankles than gout duration, regardless of serum urate level.
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T1-weighted MRI images accurately represent the volume and surface of architectural mineral damage of osteonecrosis of the femoral head: Comparison with high-resolution computed tomography.
Tristan Pascart,Julien Paccou,Thomas Colard,Laurène Norberciak,Julien Girard,Jérôme Delattre,Pierre Marchandise,J. Legrand,Guillaume Penel,Raphael Coursier,Sophie Putman,Bernard Cortet,Greet Kerckhofs,Jean-François Budzik +13 more
TL;DR: This study demonstrates that measurement of the MRI lesions provides a reliable assessment of the extent of ONFH-related architectural damage.
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Factors influencing the kinetics of MSU crystal depletion measured with dual-energy CT in patients with gout
Victor Laurent,Charlotte Jauffret,Aurore Pacaud,Vincent Ducoulombier,J. Legrand,Stéphane Verdun,Laurène Norberciak,Jean-François Budzik,Tristan Pascart +8 more
TL;DR: In patients with DECT-measured MSU crystal deposition, reaching the <5.0 mg/dL SU target provides more extensive and rapid crystal dissolution than reached the <6.0″mg/LC SU target, which was achieved by 48 (77%) and 36 (58%) patients.
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