J. Lambea
University of Zaragoza
21 Papers
75 Citations
J. Lambea is an academic researcher from University of Zaragoza. The author has contributed to research in topics: Medicine & Capecitabine. The author has an hindex of 7, co-authored 18 publications.
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Papers
Assessment of the evolution of cancer treatment therapies.
Manuel Arruebo,Nuria Vilaboa,Berta Sáez-Gutierrez,J. Lambea,Alejandro Tres,Mónica Valladares,África González-Fernández +6 more
TL;DR: A review of the evolution of cancer treatments, starting with chemotherapy, surgery, radiation and immunotherapy, and moving on to the most promising cutting-edge therapies (gene therapy and nanomedicine).
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Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer.
Simon N. Stacey,Andrei Manolescu,Patrick Sulem,Steinunn Thorlacius,Sigurjon A. Gudjonsson,Gudbjorn F. Jonsson,Margret Jakobsdottir,Jon Thor Bergthorsson,Julius Gudmundsson,Katja K.H. Aben,Luc J Strobbe,Dorine W. Swinkels,K. C. Anton van Engelenburg,Brian E. Henderson,Laurence N. Kolonel,Loic Le Marchand,Esther Millastre,Raquel Andrés,Berta Saez,J. Lambea,Javier Godino,E. Polo,Alejandro Tres,Simone Picelli,Johanna Rantala,Sara Margolin,Thorvaldur Jonsson,Helgi Sigurdsson,Thora Jonsdottir,Jon Hrafnkelsson,Jakob Johannsson,Thorarinn Sveinsson,Gardar Myrdal,Hlynur Niels Grimsson,Steinunn G Sveinsdottir,Kristin Alexiusdottir,Jona Saemundsdottir,Asgeir Sigurdsson,Jelena Kostic,Larus J. Gudmundsson,Kristleifur Kristjansson,Gisli Masson,James D. Fackenthal,Clement Adebamowo,Temidayo O. Ogundiran,Olufunmilayo I. Olopade,Christopher A. Haiman,Annika Lindblom,Jose I. Mayordomo,Lambertus A. Kiemeney,Jeffrey R. Gulcher,Thorunn Rafnar,Unnur Thorsteinsdottir,Oskar T. Johannsson,Augustine Kong,Kari Stefansson +55 more
TL;DR: A genome-wide association study of breast cancer predisposition with replication and refinement studies involving 6,145 cases and 33,016 controls identified two SNPs on 5p12 that confer risk, preferentially for ER-positive tumors.
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Phase II study of capecitabine as palliative treatment for patients with recurrent and metastatic squamous head and neck cancer after previous platinum-based treatment
Javier Martinez-Trufero,Dolores Isla,J. C. Adansa,A Irigoyen,Ricardo Hitt,I Gil-Arnaiz,J. Lambea,M J Lecumberri,Juan J. Cruz +8 more
TL;DR: Capecitabine seems to be an active, feasible and well-tolerated mode of palliative treatment for advanced HNC patients who have previously received PBT schedules.
Dendritic cell uptake of iron-based magnetic nanoparticles
Gerardo F. Goya,I. Marcos-Campos,Rodrigo Fernández-Pacheco,Berta Saez,Javier Godino,Laura Asín,J. Lambea,P. Tabuenca,Jose I. Mayordomo,Luis Larrad,M. R. Ibarra,Alejandro Tres +11 more
TL;DR: It is found that NPs are internalized in lysosomes, providing a large magnetic signal, and loading DCs with properly functionalized magnetic NPs could be a promising strategy for improved vectorization in cancer diagnosis and treatment.
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Gemcitabine/Capecitabine in Patients with Metastatic Breast Cancer Pretreated with Anthracyclines and Taxanes
Beth Andres,Jose I. Mayordomo,R. Lara,R. Lastra,Eugenia Ortega,E. Polo,J. Lambea,Dolores Isla,Alberto Saenz-Cusi,Pilar Escudero,Alejandro Tres +10 more
TL;DR: In this cohort of patients heavily pretreated with anthracyclines and taxanes, the response rate to gem citabine/capecitabine is encouraging, although response duration is limited.
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