Ivana Caputo
University of Salerno
54 Papers
443 Citations
Ivana Caputo is an academic researcher from University of Salerno. The author has contributed to research in topics: Tissue transglutaminase & Biology. The author has an hindex of 20, co-authored 49 publications. Previous affiliations of Ivana Caputo include University of Naples Federico II.
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Papers
Mammalian transglutaminases. Identification of substrates as a key to physiological function and physiopathological relevance.
Carla Esposito,Ivana Caputo +1 more
TL;DR: Data is reviewed on the properties of mammalian transglutaminases, particularly as regards their protein substrates and the relevance of transglUTaminase‐catalysed reactions in physiological and disease conditions.
205
Anti-tissue transglutaminase antibodies from coeliac patients inhibit transglutaminase activity both in vitro and in situ
Carla Esposito,F Paparo,Ivana Caputo,Mauro Rossi,Maria Maglio,Daniele Sblattero,Tarcisio Not,Raffaele Porta,S Auricchio,Roberto Marzari,R. Troncone +10 more
TL;DR: Purified CD IgA, IgG, as well as human anti-tTG monoclonal antibodies inhibited the enzymatic activity of human tTG both in vitro and in situ.
138
Humoral Immune Response to Tissue Transglutaminase Is Related to Epithelial Cell Proliferation in Celiac Disease
Maria Vittoria Barone,Ivana Caputo,Maria T. Ribecco,Maria Maglio,Roberto Marzari,Daniele Sblattero,Riccardo Troncone,Salvatore Auricchio,Carla Esposito +8 more
TL;DR: The results suggest that tTG autoantibodies per se, by interacting with the extracellular membrane-bound transglutaminase, may play an important role in epithelial cell proliferation in celiac disease.
93
Expression and enzymatic activity of small intestinal tissue transglutaminase in celiac disease
Carla Esposito,Francesco Paparo,Ivana Caputo,Raffaele Porta,V.M. Salvati,Giuseppe Mazzarella,Salvatore Auricchio,Riccardo Troncone +7 more
TL;DR: The presence in the celiac mucosa of proteins able to act as amine-donor substrates suggests that tissue transglutaminase–mediated post-translational modification of proteins cross-linked with gliadin peptides may represent a pathogenic mechanism of CD.
80
Anti-transglutaminase antibodies in non-coeliac children suffering from infectious diseases
Fortunato Ferrara,S Quaglia,Ivana Caputo,Carla Esposito,Marilena Lepretti,Serena Pastore,Rita Giorgi,Stefano Martelossi,G. Dal Molin,N Di Toro,Alessandro Ventura,Tarcisio Not +11 more
TL;DR: To compare immunological and biological characteristics of the anti‐transglutaminase antibodies derived from these children with infectious diseases with that from coeliac patients, two hundred and twenty‐two children suffering from infectious diseases were enrolled prospectively along with seven biopsy‐proven coleiacs.
79