IOVS MS 11-7777 (Article 2207) Proofs Available _______________________ Dear Author: The proofs of your article above are available for your review. Please download the file located at this URLaddress: http://rapidproof.cadmus.com/RapidProof/retrieval/index.jsp Login: [your e-mail address]Password: 99S4UntgTcU9 You will need to have Adobe Acrobat Reader software to read this file. This is free software and is availablefor user downloading at http://www.adobe.com/products/acrobat/readstep.html. If you experience technical problems, please contact Tracey Ritchey(e-mail: ritcheyt@cadmus.com; phone: 717-721-2646) This file contains: -- Instructions to Author-- Adobe Acrobat Comments and Notes Instructions-- Publication Fees and Reprint Order Form-- Page Proofs for your article, table of contents precis blurb, and author queries - containing 5 pages Please insert your comments electronically (instructions enclosed), or print the PDF proofs and add yourcomments manually. Follow the enclosed instructions for emailing, faxing, or mailing your corrections.Return all materials within 48 hours (two business days) to assure quick publication of your article. NOTE: Effective with the January 2010 issue IOVS will be available online only. No printed issues will beproduced. Printed reprints may still be ordered using the file provided. If you have any questions regarding your article, please contact me. ALWAYS INCLUDE YOURARTICLE NO. (IOVS MS 11-7777) WITH ALL CORRESPONDENCE. Cathy FreyTel: 717-721-2616Fax: 717-738-9479 or 717-738-9478freyc@cadmus.com

/pdf/investigative-ophthalmology-and-visual-science-2azo1n1ewx.pdf

Investigative Ophthalmology and Visual Science

Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm.

https://science.sciencemag.org/content/sci/287/5451/303.full.pdf

Engineering the Provitamin A (β-Carotene) Biosynthetic Pathway into (Carotenoid-Free) Rice Endosperm

The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration

https://faculty.missouri.edu/~glaserr/3700s14/Antioxidant_Carotenoids_2005.pdf

Carotenoid actions and their relation to health and disease.

The macular region of the primate retina is yellow in color due to the presence of the macular pigment, composed of two dietary xanthophylls, lutein and zeaxanthin, and another xanthophyll, meso-zeaxanthin. The latter is presumably formed from either lutein or zeaxanthin in the retina. By absorbing blue-light, the macular pigment protects the underlying photoreceptor cell layer from light damage, possibly initiated by the formation of reactive oxygen species during a photosensitized reaction. There is ample epidemiological evidence that the amount of macular pigment is inversely associated with the incidence of age-related macular degeneration, an irreversible process that is the major cause of blindness in the elderly. The macular pigment can be increased in primates by either increasing the intake of foods that are rich in lutein and zeaxanthin, such as dark-green leafy vegetables, or by supplementation with lutein or zeaxanthin. Although increasing the intake of lutein or zeaxanthin might prove to be protective against the development of age-related macular degeneration, a causative relationship has yet to be experimentally demonstrated.

Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye.

A One Year Study of the Macular Pigment: The Effect of 140 Days of a Lutein Supplement

Popular Tasks used by Researchers

How can I help with your research?

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

We encountered an error while loading the panel. Please try refreshing the page.

Something went wrong

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

Anyone with the link can view this chat. You can switch it back to private anytime.

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Hilda Joa

Author Tools

Chat about Author

Papers

A One Year Study of the Macular Pigment: The Effect of 140 Days of a Lutein Supplement