Heejin Choi
Massachusetts Institute of Technology
46 Papers
267 Citations
Heejin Choi is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Two-photon excitation microscopy & Structured light. The author has an hindex of 16, co-authored 45 publications. Previous affiliations of Heejin Choi include Nanyang Technological University & KAIST.
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Papers
Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems
Evan Murray,Jae Hun Cho,Daniel Goodwin,Taeyun Ku,Taeyun Ku,Justin Swaney,Sung-Yon Kim,Heejin Choi,Heejin Choi,Young Gyun Park,Young Gyun Park,Jeong Yoon Park,Jeong Yoon Park,Austin Hubbert,Margaret McCue,Margaret McCue,Sara Vassallo,Sara Vassallo,Naveed A. Bakh,Matthew P. Frosch,Van J. Wedeen,H. Sebastian Seung,Kwanghun Chung +22 more
TL;DR: A simple method that enables proteomic imaging for scalable, integrated, high-dimensional phenotyping of both animal tissues and human clinical samples is introduced and uniformly secures tissue architecture, native biomolecules, and antigenicity across an entire system by synchronizing the tissue preservation reaction.
451
Protection of tissue physicochemical properties using polyfunctional crosslinkers.
Young Gyun Park,Young Gyun Park,Chang Ho Sohn,Chang Ho Sohn,Ritchie Chen,Ritchie Chen,Margaret McCue,Margaret McCue,Dae Hee Yun,Dae Hee Yun,Gabrielle T. Drummond,Gabrielle T. Drummond,Taeyun Ku,Taeyun Ku,Nicholas B. Evans,Nicholas B. Evans,Hayeon Caitlyn Oak,Wendy Trieu,Heejin Choi,Heejin Choi,Xin Jin,Xin Jin,Varoth Lilascharoen,Ji Wang,Matthias C. Truttmann,Helena W. Qi,Hidde L. Ploegh,Todd R. Golub,Shih-Chi Chen,Matthew P. Frosch,Heather J. Kulik,Byung Kook Lim,Kwanghun Chung +32 more
TL;DR: SHIELD as discussed by the authors uses a flexible polyepoxide to form controlled intra-and intermolecular crosslink with biomolecules, which preserves protein fluorescence and antigenicity, transcripts and tissue architecture under a wide range of harsh conditions.
Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact Systems
Evan Murray,Jae Hun Cho,Daniel Goodwin,Taeyun Ku,Taeyun Ku,Justin Swaney,Sung-Yon Kim,Heejin Choi,Heejin Choi,Young Gyun Park,Young Gyun Park,Jeong Yoon Park,Jeong Yoon Park,Austin Hubbert,Margaret McCue,Margaret McCue,Sara Vassallo,Sara Vassallo,Naveed A. Bakh,Matthew P. Frosch,Van J. Wedeen,H. Sebastian Seung,Kwanghun Chung +22 more
- 01 Dec 2015
TL;DR: In this article, a simple method, termed SWITCH, uniformly secures tissue architecture, native biomolecules, and antigenicity across an entire system by synchronizing the tissue preservation reaction.
253
Stochastic electrotransport selectively enhances the transport of highly electromobile molecules
Sung-Yon Kim,Jae Hun Cho,Evan Murray,Naveed A. Bakh,Heejin Choi,Kimberly Ohn,Luzdary Ruelas,Austin Hubbert,Meg McCue,Sara Vassallo,Philipp J. Keller,Kwanghun Chung +11 more
TL;DR: The proposed stochastic electrotransport method uses a rotational electric field to selectively disperse highly electromobile molecules throughout a porous sample without displacing the low-electromobility molecules that constitute the sample.
239
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions
Dheeraj S. Roy,Young Gyun Park,Minyoung E. Kim,Ming Zhang,Sachie K. Ogawa,Nicholas DiNapoli,Xinyi Gu,Jae Hun Cho,Heejin Choi,Lee Kamentsky,Jared Martin,Olivia Mosto,Tomomi Aida,Kwanghun Chung,Susumu Tonegawa +14 more
TL;DR: For instance, this article reported a partial map of the engram complex for contextual fear conditioning memory by characterizing encoding activated neuronal ensembles in 247 regions using tissue phenotyping in mice.