Background Currently, it is still unclear whether adding a mucoprotective agent to a proton pump inhibitor (PPI) results in better outcomes compared with using a PPI alone in patients with post-gastric endoscopic submucosal dissection (ESD) ulcers. This study aimed to examine the efficacy of PPI alone versus combination treatment in healing of post-gastric ESD ulcers, as well as on delayed bleeding and amount of blood transfused. Methods A systematic search of MEDLINE, EMBASE, Cochrane, and ISI Web of knowledge databases, up until May 2017, for randomized trials comparing PPI alone versus PPI plus a mucoprotective drug in achieving ulcer healing in patients undergoing gastric ESD was performed. The primary outcome is scarring stage on endoscopic assessment at 4 or 8 weeks after gastric ESD. Results From an initial 3071 citations, eight articles (n = 953 lesions from 934 patients) were analyzed. Patients receiving combination treatment achieved a scarring stage significantly more often than those on a PPIs alone at 4 or 8 weeks after ESD, (risk ratio = 1.36, 95% CI; 1.06-1.75). No study reported amount of blood transfused. There were no significant between treatment-group differences in terms of delayed bleeding (risk ratio = 0.58, 95% CI; 0.17-1.99). Neither location of ulcer nor Helicobacter pylori infection was related to ulcer scarring stage. Conclusion The limited evidences suggested combination treatment may be more effective in accelerating the process of ulcer healing in patients undergoing gastric ESD than the use of PPI alone, but does not appear to alter delayed bleeding risk.

Role of mucoprotective agents in endoscopic submucosal dissection-derived ulcers: A systematic review.

Endoscopic submucosal dissection (ESD) is a new treatment method that has emerged in recent years, and it is also a technology with good clinical application prospects. Complete excision, eliminating the pain of open surgery and the removal of organs. To reduce the difficulty of gastroscopic surgery and allow doctors to complete the operation independently, it is necessary to develop a robot that can assist traditional electronic gastroscopes. Its main function is to replace the doctor’s hands on the control of the endoscope. Based on the existing technology, this paper proposes a multi-motor control method based on the EtherCAT communication protocol, which can be used for the research and development of subsequent endoscopic surgical robots.

Design Of Electrical Control System For Endoscopic Surgical Robot

Endoscopic submucosal dissection (ESD) is a new treatment method that has emerged in recent years, and it is also a technology with good clinical application prospects. Complete excision, eliminating the pain of open surgery and the removal of organs. To reduce the difficulty of gastroscopic surgery and allow doctors to complete the operation independently, it is necessary to develop a robot that can assist traditional electronic gastroscopes. Its main function is to replace the doctor’s hands on the control of the endoscope. Based on the existing technology, this paper proposes a multi-motor control method based on the EtherCAT communication protocol, which can be used for the research and development of subsequent endoscopic surgical robots. 

Submucosal injection materials other than mucosal lift.

Endoscopic submucosal dissection (ESD) is a curative treatment for early gastrointestinal (GI) cancer. Apart from ESD technique, adequate handling of resected specimen is the essential step for documenting the disease cure and planning a long-term management. In addition, post-ESD management protocol is the important strategy for patient’s safety. To current knowledge, this is the first holistic acute care recommendations in patient undergoing ESD.

Handling of Specimen and Post-ESD Management Protocol

Yu BAI,* Jian Ting CAI, You Xiang CHEN, Fei GAO, Xiao Zhong GUO, Xue Gang GUO, Ying HAN,** Jian Yu HAO, Shui Xiang HE, Ming JI, Bo JIANG, Hui Qing JIANG,*** Zhen Dong JIN,* Yan Qing LI, Zhao Shen LI,* Zhuan LIAO,* Feng LIU,* Zhi Guo LIU, He Sheng LUO, Bin LV, Nong Hua LV, Xu REN, Jian Qiu SHENG,** Rui Hua SHI,**** De An TIAN, Fang Yu WANG, Gui Qi WANG, Ai Ming YANG, Guo Xin ZHANG,***** Zhen Yu ZHANG, Fa Chao ZHI, Duo Wu ZOU,* Xiao Ping ZOU & Chinese Society of Digestive Endoscopy

Expert consensus on perioperative medications during endoscopic submucosal dissection for gastric lesions (2015, Suzhou, China).

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Expert consensus on perioperative medications during endoscopic submucosal dissection for gastric lesions (2015, Suzhou, China).