Hang Ying Tang
Li Ka Shing Faculty of Medicine, University of Hong Kong
4 Papers
5 Citations
Hang Ying Tang is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: CD8 & Peripheral blood mononuclear cell. The author has an hindex of 3, co-authored 4 publications.
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Papers
Anti–spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection
Li Liu,Qiang Wei,Qingqing Lin,Jun Fang,Haibo Wang,Hauyee Kwok,Hang Ying Tang,Kenji Nishiura,Jie Peng,Zhiwu Tan,Tongjin Wu,Ka-Wai Cheung,Kwok-Hung Chan,Xavier Alvarez,Chuan Qin,Andrew A. Lackner,Stanley Perlman,Kwok-Yung Yuen,Zhiwei Chen +18 more
TL;DR: It is determined that anti-spike IgG (S-IgG), in productively infected lungs, causes severe ALI by skewing inflammation-resolving response and providing a potential target for treatment of SARS-CoV or other virus-mediated lung injury.
Tandem bispecific neutralizing antibody eliminates HIV-1 infection in humanized mice
Xilin Wu,Xilin Wu,Jia Guo,Mengyue Niu,Mengyue Niu,Minghui An,Minghui An,Li Liu,Li Liu,Hui Wang,Xia Jin,Qi Zhang,Ka Shing Lam,Tongjin Wu,Hua Wang,Qian Wang,Yanhua Du,Jingjing Li,Lin Cheng,Hang Ying Tang,Hong Shang,Linqi Zhang,Paul Zhou,Zhiwei Chen,Zhiwei Chen +24 more
TL;DR: The results warrant the clinical development of BiIA-SG as a promising bs-bnAb–based biomedical intervention for the prevention and treatment of HIV-1 infection.
Persistent lentivirus infection induces early myeloid suppressor cells expansion to subvert protective memory CD8 T cell response
Li Liu,Qingqing Lin,Jie Peng,Jun Fang,Zhiwu Tan,Hang Ying Tang,Ka-Yi Kwan,Kenji Nishiura,Jianguo Liang,Hauyee Kwok,Zhenglong Du,Jiaze Sun,Kang Liu,Kwok-Yung Yuen,Hui Wang,Zhiwei Chen +15 more
TL;DR: MDSCs are identified as critical gatekeepers that restrain antiviral T cell memory responses, and highlight MDSCs as an important target for developing effective vaccines against chronic human infections.
6
Monoclonal antibodies specific to human Δ42PD1: A novel immunoregulator potentially involved in HIV-1 and tumor pathogenesis.
Lin Cheng,Xian Tang,Li Liu,Jie Peng,Kenji Nishiura,Allen Ka Loon Cheung,Jia Guo,Xilin Wu,Hang Ying Tang,Minghui An,Jingying Zhou,Ka-Wai Cheung,Hui Wang,Xin Yuan Guan,Zhiwei Wu,Zhiwei Chen +15 more
TL;DR: 2 high-affinity mAbs are generated from Δ42PD1-immunized mice that can be used to further investigate Δ42 PD1, a novel immune regulatory protein implicated in HIV-1 and tumor pathogenesis as well as other immune diseases.