Guohong Wei
Sun Yat-sen University
12 Papers
17 Citations
Guohong Wei is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Thyroid cancer & Biology. The author has an hindex of 6, co-authored 12 publications.
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Papers
Identification and functional characterization of mutations in LPL gene causing severe hypertriglyceridaemia and acute pancreatitis
Peng Han,Guohong Wei,Ke Cai,Xi Xiang,Wang Ping Deng,Yan Bing Li,Shan Kuang,Zhanying Dong,Tianyu Zheng,Yonglun Luo,Junnian Liu,Yuanning Guan,Chen Li,Subrata Kumar Dey,Zhihong Liao,Santasree Banerjee +15 more
TL;DR: Three mutations in LPL gene which causes severe hypertriglyceridaemia with acute pancreatitis in Chinese patients are identified and the significance of whole exome sequencing for identifying the candidate gene and disease‐causing mutation is described.
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Downregulation of Bcl-2 Expression by miR-34a Mediates Palmitate-Induced Min6 Cells Apoptosis
TL;DR: It is concluded that direct suppression of Bcl-2 by miR-34a accounts for palmitate-induced increased apoptosis rate in pancreatic β-cell.
Single‐cell transcriptomic landscape reveals the differences in cell differentiation and immune microenvironment of papillary thyroid carcinoma between genders
Miaoguan Peng,Guohong Wei,Yunjian Zhang,Hai Li,Yingrong Lai,Yan Guo,Yuxin Chen,Liehua Liu,Haipeng Xiao,Hongyu Guan,Yanbing Li +10 more
TL;DR: Detailed differences in cell clusters and immune microenvironment in PTC according to gender at the single-cell level were revealed, which provided new insights into the understanding of the impact of gender on PTC.
miR-101 inhibits cell proliferation by targeting Rac1 in papillary thyroid carcinoma
Xiaojie Lin,Hongyu Guan,Hai Li,Liehua Liu,Juan Liu,Guohong Wei,Zhimin Huang,Zhihong Liao,Yanbing Li +8 more
TL;DR: Investigating the role of microRNA-101 in PTC via targeting of Ras-related C3 botulinum toxin substrate 1 showed that miR-101 was significantly downregulated in P TC tissues compared with adjacent normal tissues, providing a better understanding of miRNA-modulated signaling networks for future cancer therapeutics.
Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway
Xing Zhong,Lingling Xiu,Guohong Wei,Tianrong Pan,Yuan-Yuan Liu,Lei Su,Yanbing Li,Haipeng Xiao +7 more
TL;DR: Findings indicate that bezafibrate inbibits palmitate-induced apoptosis via the NF-κB signaling pathway is a new strategy to attenuate bone loss associated with high fat diet beyond its lipid-lowering actions.