Franz Rödel
Goethe University Frankfurt
190 Papers
1.5K Citations
Franz Rödel is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Medicine & Survivin. The author has an hindex of 48, co-authored 174 publications. Previous affiliations of Franz Rödel include German Cancer Research Center & University of Oxford.
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Papers
Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer.
Panagiotis Balermpas,Yvonne Michel,Jens Wagenblast,Oliver Seitz,Christian Weiss,Franz Rödel,Claus Rödel,Emmanouil Fokas +7 more
TL;DR: The positive correlation between a high number of infiltrating CD3+ and CD8+ cells and clinical outcome indicates that TILs may have a beneficial role in HNSCC patients and may serve as a biomarker to identify patients likely to benefit from definitive CRT.
Radiation sensitivity of human and murine peripheral blood lymphocytes, stem and progenitor cells.
TL;DR: The data indicate considerable differences in radiosensitivity of bone marrow and blood normal and malignant cell populations, which are discussed in the light of differential radiation responses resulting in hematotoxicity and related clinical implications.
212
Radiobiological mechanisms in inflammatory diseases of low-dose radiation therapy.
TL;DR: Data and models revealing aspects of the mechanisms underlying the anti-inflammation induced by low doses of X-irradiation may serve as a basis for systematic analyses, necessary to optimize LD-RT in clinical practice.
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Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer.
Adele M. Nicolas,Marina Pesic,Esther Engel,Paul Ziegler,Markus Diefenhardt,Kilian B. Kennel,Florian Buettner,Claire Conche,Valentina Petrocelli,Eiman Elwakeel,Andreas Weigert,Anna Zinoveva,Max Fleischmann,Björn Häupl,Cem Karakütük,Hanibal Bohnenberger,Mohammed H. Mosa,Lars Kaderali,Jochen Gaedcke,B. Michael Ghadimi,Franz Rödel,Melek C. Arkan,Thomas Oellerich,Claus Rödel,Emmanouil Fokas,Florian R. Greten +25 more
TL;DR: In this article , the role of interleukin-1α signaling in the development of cancer-associated fibroblasts with poor chemoradiotherapy response was investigated.
195
Modulation of Inflammatory Immune Reactions by Low-Dose Ionizing Radiation: Molecular Mechanisms and Clinical Application
Franz Rödel,Benjamin Frey,Udo S. Gaipl,Ludwig Keilholz,C. Fournier,Katrin Manda,Helmut Schöllnberger,Guido Hildebrandt,Claus Rödel +8 more
TL;DR: Recent developments in the understanding of low-dose irradiation immune modulating properties with special emphasis on discontinuous dose response relationships are discussed.
184