Federica Moalli
University of Bern
44 Papers
222 Citations
Federica Moalli is an academic researcher from University of Bern. The author has contributed to research in topics: Innate immune system & PTX3. The author has an hindex of 24, co-authored 43 publications. Previous affiliations of Federica Moalli include Vita-Salute San Raffaele University & University of Milan.
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Papers
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps
Sébastien Jaillon,Giuseppe Peri,Yves Delneste,Isabelle Frémaux,Andrea Doni,Federica Moalli,Cecilia Garlanda,Luigina Romani,Hugues Gascan,Silvia Bellocchio,Silvia Bozza,Marco A. Cassatella,Pascale Jeannin,Alberto Mantovani +13 more
TL;DR: The long pentraxin (PTX) 3 is produced by macrophages and myeloid dendritic cells in response to Toll-like receptor agonists and represents a nonredundant component of humoral innate immunity against selected pathogens.
Deficiency of the Long Pentraxin PTX3 Promotes Vascular Inflammation and Atherosclerosis
Giuseppe Danilo Norata,Patrizia Marchesi,Vivek Krishna Pulakazhi Venu,Fabio Pasqualini,Achille Anselmo,Federica Moalli,Irene Pizzitola,Cecilia Garlanda,Alberto Mantovani,Alberico L. Catapano +9 more
TL;DR: PTX3 has atheroprotective effects in mice, which, in light of the cardioprotective effects recently reported, suggests a cardiovascular protective function of the long pentraxin 3 through the modulation of the immunoinflammatory balance in the cardiovascular system.
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Role of complement and Fcγ receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus
Federica Moalli,Andrea Doni,Livija Deban,Teresa Zelante,S. Zagarella,Barbara Bottazzi,Luigina Romani,Alberto Mantovani,Cecilia Garlanda +8 more
TL;DR: The protective activity of exogenous PTX3 against A fumigatus was abolished in FcR common γ chain-deficient mice, indicating that the opsonic and antifungal activity ofPTX3 is at the crossroad between complement, complement receptor 3-, and FcγR-mediated recognition.
214
The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity.
Barbara Bottazzi,Cecilia Garlanda,Alessia Cotena,Federica Moalli,Sébastien Jaillon,Livija Deban,Alberto Mantovani +6 more
TL;DR: The studies on PTX3 are reviewed, which emphasize the complexity and complementarity of the crosstalk between the cellular and humoral arms of innate immunity.
190
Dynamics and genomic landscape of CD8 + T cells undergoing hepatic priming
Alexandre P. Benechet,Giorgia De Simone,Pietro Di Lucia,Francesco Cilenti,Giulia Barbiera,Nina Le Bert,Valeria Fumagalli,Eleonora Lusito,Federica Moalli,Valentina Bianchessi,Francesco Andreata,Paola Zordan,Elisa Bono,Leonardo Giustini,Weldy V. Bonilla,Camille Blériot,Kamini Kunasegaran,Gloria González-Aseguinolaza,Daniel D. Pinschewer,Patrick T F Kennedy,Luigi Naldini,Mirela Kuka,Florent Ginhoux,Florent Ginhoux,Alessio Cantore,Antonio Bertoletti,Antonio Bertoletti,Renato Ostuni,Luca G. Guidotti,Matteo Iannacone +29 more
TL;DR: It is shown that priming by Kupffer cells, which is not natural targets of hepatitis B, leads to differentiation of CD8+ T cells into effector cells that form dense, extravascular clusters of immotile cells scattered throughout the liver.
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