Edith N.G. Houben
VU University Amsterdam
58 Papers
237 Citations
Edith N.G. Houben is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Secretion & Inner membrane. The author has an hindex of 34, co-authored 54 publications. Previous affiliations of Edith N.G. Houben include VU University Medical Center & Stockholm University.
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Papers
Systematic genetic nomenclature for type VII secretion systems.
Wilbert Bitter,Edith N.G. Houben,Darria Bottai,Priscille Brodin,Eric J. Brown,Jeffery S. Cox,Keith M. Derbyshire,Sarah M. Fortune,Lian-Yong Gao,Jun Liu,Nicolaas C. Gey van Pittius,Alexander S. Pym,Eric J. Rubin,David R. Sherman,Stewart T. Cole,Roland Brosch +15 more
TL;DR: The systematic genetic nomenclature for type VII secretion systems is described, which indicates a clear hierarchy of secretion systems and indicates the dominance of type VII in the immune system.
Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins.
Musa Sani,Edith N.G. Houben,Jeroen Geurtsen,Jason Pierson,Karin de Punder,Maaike van Zon,Brigitte Wever,Sander R. Piersma,Connie R. Jimenez,Mamadou Daffé,Ben J. Appelmelk,Wilbert Bitter,Nicole N. van der Wel,Peter J. Peters,Peter J. Peters +14 more
TL;DR: Using plunge freezing cryo-electron microscopy technique, a direct visualization of the mycobacterial capsular layer as a labile structure that contains ESX-1-secreted proteins is shown.
Biogenesis of inner membrane proteins in Escherichia coli
TL;DR: Evidence obtained in recent years indicates that most, if not all, inner membrane proteins require the assistance of protein factors to reach their native conformation in the membrane.
262
Dendritic Cell Stimulation by Mycobacterial Hsp70 Is Mediated Through CCR5
R. Andres Floto,Paul A. MacAry,Paul A. MacAry,Jessica M. Boname,Tan Suet Mien,Beate Kampmann,James R. Hair,Oh Seen Huey,Edith N.G. Houben,Jean Pieters,Cheryl L. Day,Wulf Oehlmann,Mahavir Singh,Kenneth G. C. Smith,Paul J. Lehner +14 more
TL;DR: It is found that CCR5 acts as a pattern-recognition receptor for myHsp70, which may have implications for both the pathophysiology of tuberculosis and the use of myHsps in tumor-directed immunotherapy.
179
Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria.
Louis S. Ates,Roy Ummels,Susanna Commandeur,Robert van der Weerd,Marion Sparrius,Eveline M. Weerdenburg,Marina Alber,Rainer Kalscheuer,Sander R. Piersma,Abdallah M. Abdallah,Moataz Abd El Ghany,Alyaa M. Abdel-Haleem,Arnab Pain,Connie R. Jimenez,Wilbert Bitter,Wilbert Bitter,Edith N.G. Houben +16 more
TL;DR: A model in which the ESX-5 system is responsible for the transport of cell envelope proteins that are required for nutrient uptake is proposed, which might in this way compensate for the lack of MspA-like porins in slow-growing mycobacteria.