Dirk J. Ruiter
Radboud University Nijmegen Medical Centre
302 Papers
6.4K Citations
Dirk J. Ruiter is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Melanoma & Metastasis. The author has an hindex of 77, co-authored 301 publications. Previous affiliations of Dirk J. Ruiter include Praxis & Radboud University Nijmegen.
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Papers
How schema and novelty augment memory formation.
Marlieke T. R. van Kesteren,Marlieke T. R. van Kesteren,Dirk J. Ruiter,Guillén Fernández,Guillén Fernández,Richard N. Henson +5 more
TL;DR: Lesion and neuroimaging findings in animals and humans that relate to the apparent paradoxical relationship between schema and novelty and a framework relating key brain regions in medial temporal lobe and medial prefrontal cortex during encoding, consolidation and retrieval of information as a function of its congruency with existing information represented in neocortex are reviewed.
835
•Journal Article
Maturation of Dendritic Cells Is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients
I. Jolanda M. de Vries,W. Joost Lesterhuis,Nicole M. Scharenborg,Linda P. H. Engelen,Dirk J. Ruiter,Marie-Jeanne P. Gerritsen,Sandra Croockewit,Cedrik M. Britten,Ruurd Torensma,Gosse J. Adema,Carl G. Figdor,Cornelis J. A. Punt +11 more
TL;DR: It is concluded that mature DC are superior to immature DC in the induction of immunological responses in melanoma patients, which may translate into improved clinical results.
Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial.
Alexander M.M. Eggermont,Stefan Suciu,Rona M. MacKie,Wlodzimierz Ruka,Alessandro Testori,Wim H. J. Kruit,Cornelis J. A. Punt,Michelle Delauney,François Sales,Gerard Groenewegen,Dirk J. Ruiter,Izabella Jagiello,Konstantin Stoitchkov,Ulrich Keilholz,Danielle Lienard +14 more
TL;DR: Interferon alfa as used in the regimens studied does not improve outcome for patients with stage IIb/III melanomas, and cannot be recommended.
324
Differential roles for medial prefrontal and medial temporal cortices in schema-dependent encoding: From congruent to incongruent
Marlieke T. R. van Kesteren,Marlieke T. R. van Kesteren,Sarah F. Beul,Sarah F. Beul,Atsuko Takashima,Richard N. Henson,Dirk J. Ruiter,Guillén Fernández,Guillén Fernández +8 more
TL;DR: These findings show that enhanced memory for more congruent information is mediated by the mPFC, which is hypothesised to guide integration of new information into a pre-existing schema represented in cortical areas, whileMemory for more incongruent information relies instead on automatic encoding of arbitrary associations by the MTL.
315
•Journal Article
Monoclonal antibody PAL-E specific for endothelium.
TL;DR: Based on immunoelectronmicroscopic observations, the antigenic determinant recognized by PAL-E is associated with endothelial vesicles and is a new staining reagent for endothelium in frozen sections.
287