7 Papers
12 Citations
Di Yang is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Osseointegration & Osteosarcoma. The author has an hindex of 5, co-authored 7 publications.
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Papers
HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma.
Xin Xiao,Wei Wang,Yuqian Li,Di Yang,Xiaokang Li,Chao Shen,Yan Liu,Xianzhu Ke,Shuo Guo,Zheng Guo +9 more
TL;DR: It is shown that chemotherapy agents can induce HSP90AA1 expression in osteosarcoma cells and HSP 90AA1, acting as an important regulator of autophagy, is a critical factor in the development of osteosARcoma chemoresistance both in vitro and in vivo.
Biofunctional magnesium coated Ti6Al4V scaffold enhances osteogenesis and angiogenesis in vitro and in vivo for orthopedic application.
Peng Gao,Peng Gao,Bo Fan,Xiaoming Yu,Xiaoming Yu,Wenwen Liu,Jie Wu,Lei Shi,Di Yang,Lili Tan,Peng Wan,Yulin Hao,Shujun Li,Wentao Hou,Ke Yang,Xiaokang Li,Zheng Guo +16 more
TL;DR: This study enlarges the application scope of magnesium and provides an optional choice to the conventional porous Ti6Al4V scaffold with enhanced osteogenesis and angiogenesis for further orthopedic applications.
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MicroRNA-495 suppresses osteosarcoma invasion and migration by targeting HSP90AA1
Xin Xiao,Wei Wang,Xiaokang Li,Yuqian Li,Di Yang,Chao Shen,Peng Gao,Jie Wu,Shuo Guo,Zheng Guo +9 more
TL;DR: It is proved for the first time that miR-495 acts as a tumor suppressor in osteosarcoma and inhibits cell migration and invasion by targeting HSP90AA1, thus offering a promising therapeutic target for osteosARcoma treatment.
Comparative effectiveness of PEEK rods versus titanium alloy rods in cervical fusion in a new sheep model
Jie Wu,Lei Shi,Yanjun Pei,Di Yang,Peng Gao,Xin Xiao,Shuo Guo,Minghui Li,Xiaokang Li,Zheng Guo +9 more
TL;DR: PEEK rods can be used safely in a sheep model of anterior–posterior cervical fixation and compared to traditional titanium rods, earlier and more evident bone fusion was found in the PEEK rods group.
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A vessel subtype beneficial for osteogenesis enhanced by strontium-doped sodium titanate nanorods by modulating macrophage polarization
Shuo Guo,Dongmei Yu,Xin Xiao,Wenwen Liu,Zhigang Wu,Lei Shi,Quanming Zhao,Di Yang,Yajie Lu,Xinghui Wei,Zhen Tang,Ning Wang,Xiaokang Li,Yong Han,Zheng Guo +14 more
TL;DR: This study fabricated a newly sustained release system consisting of Sr ion-loaded sodium titanate nanorods (STSr) and studied its effect on angiogenesis by regulating macrophage subtypes, which serves as a basis for the clinical application of novel functional topography surfaces fabricated on titanium.