Deborah Commins
University of Southern California
38 Papers
358 Citations
Deborah Commins is an academic researcher from University of Southern California. The author has contributed to research in topics: Acquired immunodeficiency syndrome (AIDS) & Medicine. The author has an hindex of 19, co-authored 38 publications. Previous affiliations of Deborah Commins include University of California, Los Angeles.
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Papers
The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-Associated Neurocognitive Impairment
Benjamin B. Gelman,Tiansheng Chen,Joshua G. Lisinicchia,Vicki M. Soukup,J. Russ Carmical,Jonathan M. Starkey,Eliezer Masliah,Deborah Commins,Dianne Brandt,Igor Grant,Elyse J. Singer,Andrew J. Levine,Jeremy A. Miller,Jessica M. Winkler,Howard S. Fox,Bruce A. Luxon +15 more
TL;DR: Two patterns of brain gene expression suggest that more than one pathophysiological process occurs in HIV-1-associated neurocognitive impairment, and array results suggest that modulation of transvascular signaling is a potentially promising approach.
Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains.
Adarsh M. Kumar,J. B. Fernandez,Elyse J. Singer,Deborah Commins,Drenna Waldrop-Valverde,Raymond L. Ownby,Mahendra Kumar +6 more
TL;DR: Findings suggest widespread deficits in dopamine in different brain regions of HIV-1-infected cases, and that these deficits may be the results of HIV -1-induced neurodegeneration in the subcortical regions of human brain.
Editorial NeuroAIDS review
Paul Shapshak,Pandjassarame Kangueane,Robert K. Fujimura,Deborah Commins,Francesco Chiappelli,Elyse J. Singer,Andrew J. Levine,Alireza Minagar,Francis J. Novembre,Charurut Somboonwit,Avindra Nath,John T. Sinnott +11 more
TL;DR: Highlights from the spectrum of NeuroAIDS research predominantly related to human immunodeficiency virus-1 clade B (HIV-1B) are reviewed below.
Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease
Andrew J. Levine,Jeremy A. Miller,Paul Shapshak,Benjamin B. Gelman,Elyse J. Singer,Charles H. Hinkin,Deborah Commins,Susan Morgello,Igor Grant,Steve Horvath +9 more
TL;DR: While under-powered, this study identified possible biologically-relevant networks correlated with NCI in HIV, and common networks shared with AD, opening new avenues for inquiry in the investigation of HAND neuropathogenesis.
Pathology of primary central nervous system lymphoma.
TL;DR: The author provides concise descriptions of the pathological features of both common and uncommon types of PCNSL while discussing issues such as the confusion surrounding histological classification ofPCNSLs, problems related to intraoperative diagnosis, and the appropriate diagnostic work up.