D.T. Weldon
Veterans Health Administration
15 Papers
221 Citations
D.T. Weldon is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: (+)-Naloxone & Palatability. The author has an hindex of 11, co-authored 15 publications. Previous affiliations of D.T. Weldon include University of Minnesota.
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Papers
Effect of naloxone on intake of cornstarch, sucrose, and polycose diets in restricted and nonrestricted rats
TL;DR: The effect of the opioid receptor antagonist naloxone on intake of three isocaloric diets containing cornstarch, sucrose, or Polycose as the predominant carbohydrate in ad libitum-fed and food-restricted rats lends further support to the notion that opioids are involved in some other component of feeding than that induced by energy needs.
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Naloxone administration following operant training of sucrose/water discrimination in the rat
Eugene O'Hare,James P. Cleary,James P. Cleary,Peter J. Bartz,D.T. Weldon,D.T. Weldon,Charles J. Billington,Allen S. Levine +7 more
TL;DR: The suppression of food intake observed following naloxone administration has often been ascribed to palatability or taste, but no significant differences were observed between the sucrose concentration gradients obtained under saline and those obtained under n aloxone, suggesting that the anorectic effect of nalOXone is not primarily determined by discrimination of sweet taste.
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•Journal Article
New insights into the neuropathology and cell biology of Alzheimer's disease.
TL;DR: Results from the laboratory suggest that fibrillar A beta activates microglia and astrocytes upon injection into the rat brain, and these data support the hypothesized role of inflammatory mechanisms in AD neurotoxicity.
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Age-related changes in brain proDynorphin gene expression in the rat.
Catherine M. Kotz,Catherine M. Kotz,D.T. Weldon,Charles J. Billington,Charles J. Billington,Allen S. Levine +5 more
TL;DR: An age-related decrease in the synthesis of dynorphin in two brain regions strongly associated with feeding behavior, and an increase in dynorphIn synthesis in a brain region associated with learning and memory are suggested.
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Measuring Delirium Severity in Older General Hospital Inpatients Without Dementia: The Delirium Severity Scale
K M Bettin,Gabe J. Maletta,Maurice W Dysken,Kristin M. Jilk,D.T. Weldon,Michael A. Kuskowski,John R. Mach +6 more
TL;DR: The Delirium Severity Scale shows promise as a valid and reliable measure sensitive to changing symptom severity and is significantly inversely correlated with experts' quantitative ratings of severity at all three time-points examined.
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