Chenxu Qu
University of Southern California
14 Papers
15 Citations
Chenxu Qu is an academic researcher from University of Southern California. The author has contributed to research in topics: Colorectal cancer & Medicine. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Chenxu Qu include University of Virginia & City of Hope National Medical Center.
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Papers
The Prognostic Implications of Tumor Infiltrating Lymphocytes in Colorectal Cancer: A Systematic Review and Meta-Analysis.
TL;DR: The results demonstrate that high levels of generalized TILS as compared to low levels had an improved overall survival (OS) and suggest that TILs and specific TIL subsets serve as prognostic biomarkers for colorectal cancer.
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Ceres Fernandez-Rozadilla,Maria Timofeeva,Zhishan Chen,Philip J. Law,Minta Thomas,Stephanie L. Schmit,Virginia Díez-Obrero,Li Hsu,Juan Fernández-Tajes,Claire Palles,Kitty Sherwood,Sarah Briggs,Victoria Svinti,K. Donnelly,Susan M. Farrington,James P. Blackmur,P G Vaughan-Shaw,Xiao-Ou Shu,Jirong Long,Qiuyin Cai,Xingyi Guo,Yingchang Lu,Peter Broderick,James B. Studd,Jeroen R. Huyghe,Tabitha A. Harrison,David V. Conti,Christopher H. Dampier,Matt Devall,Fredrick R. Schumacher,Marilena Melas,Gad Rennert,Mireia Obón-Santacana,Vicente Martín Sánchez,Ferran Moratalla-Navarro,Jae Hwan Oh,Jeongseon Kim,Sun Ha Jee,Keum Ji Jung,Sun-Seog Kweon,Min-Ho Shin,Aesun Shin,Yoon Ok Ahn,Dong-Hyun Kim,Isao Oze,Wanqing Wen,Keitaro Matsuo,Koichi Matsuda,Chizu Tanikawa,Zefang Ren,Yu-Tang Gao,Wei Hua Jia,John L. Hopper,Mark A. Jenkins,Aung Ko Win,Rish K. Pai,Jane C. Figueiredo,Robert W. Haile,Steven Gallinger,Michael O. Woods,Polly A. Newcomb,David Duggan,Jeremy Peter Cheadle,Richard Kaplan,Tim Maughan,Rachel Kerr,David Kerr,Iva Kirac,Jan Böhm,Lukka-Pekka Mecklin,Pekka Jousilahti,Paul Knekt,Lauri A. Aaltonen,Harri Rissanen,Eero Pukkala,Johan Holmberg Eriksson,Tatiana Cajuso,Ulrika A. Hänninen,Johanna Kondelin,Kimmo Palin,Tomas Tanskanen,Laura Renkonen-Sinisalo,Brent W. Zanke,Satu Männistö,Demetrius Albanes,Stephanie J. Weinstein,Edward A. Ruiz-Narváez,Julie K. Palmer,C. D. Buchanan,Elizabeth Platz,Kala Visvanathan,Cornelia M. Ulrich,Erin M. Siegel,Stefanie Brezina,Andrea Gsur,Peter J. Campbell,Jenny Chang-Claude,Michael Hoffmeister,Hermann Brenner,Martha L. Slattery,John D. Potter,Konstantinos K. Tsilidis,Mathias Schulze,Marc J. Gunter,Neil Murphy,A. Castells,Sergi Castellví-Bel,Leticia Moreira,Volker Arndt,Anna Shcherbina,Mariana C. Stern,Bens Pardamean,Timothy E. Bishop,Graham Blakemore Giles,Melissa C. Southey,Gregory Idos,Kevin McDonnell,Zomoroda Abu-Ful,Joel K. Greenson,Katerina Shulman,Flavio Lejbkowicz,Kenneth Offit,Robert S. Steinfelder,Temitope O. Keku,Bethany Van Guelpen,Thomas J. Hudson,Heather Hampel,Rachel Pearlman,Sonja I. Berndt,Richard H. Hayes,Marie Martinez,Sushma S. Thomas,Douglas A. Corley,Paul D.P. Pharoah,Susanna C. Larsson,Yun Yen,Heinz-Josef Lenz,Emily White,Li Xin Li,Kimberly F. Doheny,Elizabeth W. Pugh,Tameka Shelford,Andrew Chan,Marcia Cruz-Correa,Annika Lindblom,David J. Hunter,Amit Joshi,Clemens Schafmayer,Peter C. Scacheri,Anshul Kundaje,Deborah A. Nickerson,Robert Schoen,Jochen Hampe,Zsofia K. Stadler,Pavel Vodicka,Ludmila Vodickova,Veronika Vymetalkova,Nickolas Papadopoulos,Chistopher Edlund,W. James Gauderman,D. Thomas,David Shibata,Amanda E. Toland,Sanford D. Markowitz,Andre E. Kim,Stephen J. Chanock,Fränzel J.B. Van Duijnhoven,Edith F. Feskens,Lori C. Sakoda,Manuela Gago-Dominguez,Alicja Wolk,Alessio Naccarati,Barbara Pardini,Liesel M. FitzGerald,Soo-Chin Lee,Shuji Ogino,Stephanie A. Bien,Charles Kooperberg,Christopher Li,Yi-Kuei Lin,R Reid Prentice,Conghui Qu,Stéphane Bézieau,Catherine M. Tangen,Elaine R. Mardis,Taiki Yamaji,Norie Sawada,Motoki Iwasaki,Christopher A. Haiman,Loic Le Marchand,Anna C. Wu,Chenxu Qu,Caroline McNeil,Gerhard J. R. Coetzee,Caroline Hayward,I. A. Deary,Sarah Harris,Evropi Theodoratou,Stuart Reid,Marion Walker,Li-Yin Ooi,Victor Moreno,Graham Casey,Stephen B. Gruber,Ian Tomlinson,Wei Zheng,Malcolm G. Dunlop,Richard S. Houlston,Ulrike Peters +208 more
TL;DR: This article conducted a genome-wide association study meta-analysis of 100,204 colorectal cancer cases and 154,587 controls of European and east Asian ancestry, identifying 205 independent risk associations, of which 50 were unreported.
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.
Stephanie A. Bien,Stephanie A. Bien,Yu Ru Su,Yu Ru Su,David V. Conti,David V. Conti,Tabitha A. Harrison,Tabitha A. Harrison,Conghui Qu,Conghui Qu,Xingyi Guo,Xingyi Guo,Yingchang Lu,Yingchang Lu,Demetrius Albanes,Paul L. Auer,Paul L. Auer,Barbara L. Banbury,Barbara L. Banbury,Sonja I. Berndt,Stéphane Bezieau,Hermann Brenner,Daniel D. Buchanan,Bette J. Caan,Bette J. Caan,Peter T. Campbell,Peter T. Campbell,Christopher S. Carlson,Christopher S. Carlson,Andrew T. Chan,Andrew T. Chan,Andrew T. Chan,Jenny Chang-Claude,Jenny Chang-Claude,Jenny Chang-Claude,Sai Chen,Sai Chen,Charles M. Connolly,Charles M. Connolly,Douglas F. Easton,Douglas F. Easton,Edith J.M. Feskens,Edith J.M. Feskens,Steven Gallinger,Steven Gallinger,Graham G. Giles,Graham G. Giles,Graham G. Giles,Marc J. Gunter,Marc J. Gunter,Jochen Hampe,Jochen Hampe,Jeroen R. Huyghe,Jeroen R. Huyghe,Michael Hoffmeister,Michael Hoffmeister,Thomas J. Hudson,Thomas J. Hudson,Thomas J. Hudson,Eric J. Jacobs,Eric J. Jacobs,Mark A. Jenkins,Mark A. Jenkins,Ellen Kampman,Ellen Kampman,Hyun Min Kang,Hyun Min Kang,Tilman Kühn,Tilman Kühn,Sébastien Küry,Flavio Lejbkowicz,Flavio Lejbkowicz,Loic Le Marchand,Loic Le Marchand,RL Milne,RL Milne,RL Milne,Li Li,Li Li,Christopher I. Li,Christopher I. Li,Annika Lindblom,Annika Lindblom,Annika Lindblom,Noralane M. Lindor,Noralane M. Lindor,Vicente Martín,Vicente Martín,Caroline McNeil,Caroline McNeil,Marilena Melas,Marilena Melas,Victor Moreno,Polly A. Newcomb,Polly A. Newcomb,Kenneth Offit,Kenneth Offit,Paul D.P. Pharaoh,Paul D.P. Pharaoh,John D. Potter,John D. Potter,Chenxu Qu,Chenxu Qu,Elio Riboli,Elio Riboli,Gad Rennert,Gad Rennert,Núria Sala,Clemens Schafmayer,Peter C. Scacheri,Peter C. Scacheri,Stephanie L. Schmit,Gianluca Severi,Gianluca Severi,Martha L. Slattery,Martha L. Slattery,Joshua D. Smith,Joshua D. Smith,Antonia Trichopoulou,Antonia Trichopoulou,Rosario Tumino,Cornelia M. Ulrich,Cornelia M. Ulrich,Fränzel J. B. van Duijnhoven,Fränzel J. B. van Duijnhoven,Bethany Van Guelpen,Bethany Van Guelpen,Stephanie J. Weinstein,Emily White,Emily White,Alicja Wolk,Alicja Wolk,Alicja Wolk,Michael O. Woods,Michael O. Woods,Anna H. Wu,Anna H. Wu,Gonçalo R. Abecasis,Gonçalo R. Abecasis,Graham Casey,Graham Casey,Deborah A. Nickerson,Deborah A. Nickerson,Stephen B. Gruber,Stephen B. Gruber,Li Hsu,Li Hsu,Wei Zheng,Wei Zheng,Ulrike Peters,Ulrike Peters +150 more
TL;DR: PendiXcan as mentioned in this paper uses cis-regulatory variant predictors to impute expression and perform gene-level association tests in GWAS without directly measured transcriptomes, finding statistically significant associations using colon transcriptome models with TRIM4 and PYGL.
•Journal Article
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (vol 138, pg 307, 2019)
Stephanie A. Bien,Yu-Ru Su,David V. Conti,Tabitha A. Harrison,Conghui Qu,Xingyi Guo,Yingchang Lu,Demetrius Albanes,Paul L. Auer,Barbara L. Banbury,Sonja I. Berndt,Stéphane Bézieau,Hermann Brenner,Daniel D. Buchanan,Bette J. Caan,Peter T. Campbell,Christopher S. Carlson,Andrew T. Chan,Jenny Chang-Claude,Sai Chen,Charles M. Connolly,Douglas F. Easton,Edith J. M. Feskens,Steven Gallinger,Graham G. Giles,Marc J. Gunter,Jochen Hampe,Jeroen R. Huyghe,Michael Hoffmeister,Thomas J. Hudson,Eric J. Jacobs,Mark A. Jenkins,Ellen Kampman,Hyun Min Kang,Tilman Kuehn,Sébastien Küry,Flavio Lejbkowicz,Loic Le Marchand,Roger L. Milne,Li Li,Christopher I. Li,Annika Lindblom,Noralane M. Lindor,Vicente Martín,Caroline McNeil,Marilena Melas,Victor Moreno,Polly A. Newcomb,Kenneth Offit,Paul D.P. Pharaoh,John D. Potter,Chenxu Qu,Elio Riboli,Gad Rennert,Núria Sala,Clemens Schafmayer,Peter C. Scacheri,Stephanie L. Schmit,Gianluca Severi,Martha L. Slattery,Joshua D. Smith,Antonia Trichopoulou,Rosario Tumino,Cornelia M. Ulrich,Fraenzel Jb van Duijnhoven,Bethany Van Guelpen,Stephanie J. Weinstein,Emily White,Alicja Wolk,Michael O. Woods,Anna H. Wu,Gonçalo R. Abecasis,Graham Casey,Deborah A. Nickerson,Stephen B. Gruber,Li Hsu,Wei Zheng,Ulrike Peters +77 more
TL;DR: This study is the first to implement PrediXcan in a large colorectal cancer study and findings highlight the utility of integrating transcriptome data in GWAS for discovery of, and biological insight into, risk loci.
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The relationship between health belief and sleep quality of Chinese college students: The mediating role of physical activity and moderating effect of mobile phone addiction
TL;DR: Wang et al. as mentioned in this paper analyzed the data collected from survey questionnaires, which were filled out by 1,019 college students (including 429 males and 590 females) from five comprehensive colleges and universities from March 2022 to April 2022.
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