Cheng Hock Toh
University of Liverpool
152 Papers
2K Citations
Cheng Hock Toh is an academic researcher from University of Liverpool. The author has contributed to research in topics: Disseminated intravascular coagulation & Medicine. The author has an hindex of 36, co-authored 132 publications. Previous affiliations of Cheng Hock Toh include Royal Liverpool and Broadgreen University Hospital NHS Trust & Royal Liverpool University Hospital.
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Papers
Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation.
TL;DR: In this paper, the authors presented a study on the effects of haematology drugs on the development of heart disease in patients with hemophilia and showed that they are useful in the treatment of heart failure.
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•Journal Article
Towards Definition, Clinical and Laboratory Criteria, and a Scoring System for Disseminated Intravascular Coagulation* On behalf of the Scientific Subcommittee on Disseminated Intravascular Coagulation (DIC) of the ISTH
TL;DR: This poster presents a poster presented at the European Hemophilia and Vascular Biology Conference in Brussels, Belgium, which aims to present a probabilistic picture of the immune system’s response to blood clotting disorders.
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Guidelines for the diagnosis and management of disseminated intravascular coagulation
TL;DR: Transfusion of platelets or plasma (components) in patients with DIC should not primarily be based on laboratory results and should in general be reserved for patients who present with bleeding, but should be considered in those with active bleeding and in those requiring an invasive procedure.
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A Randomized Trial of Genotype-Guided Dosing of Warfarin
Munir Pirmohamed,Girvan Burnside,Niclas Eriksson,Andrea L. Jorgensen,Cheng Hock Toh,Toby Nicholson,Patrick Kesteven,Christina Christersson,Bengt Wahlström,Christina Stafberg,J. Eunice Zhang,Julian B. S. Leathart,Hugo Kohnke,Anke H. Maitland-van der Zee,Paula R Williamson,Ann K. Daly,Peter Avery,Farhad Kamali,Mia Wadelius,Abstr Act +19 more
TL;DR: Pharmacogenetic-based dosing was associated with a higher percentage of time in the therapeutic INR range than was standard dosing during the initiation of warfarin therapy.
Circulating histones are mediators of trauma-associated lung injury.
Simon T. Abrams,Nan Zhang,Joanna Manson,Tingting Liu,Caroline Dart,Florence Baluwa,Susan Siyu Wang,Karim Brohi,Anja Kipar,Weiping Yu,Guozheng Wang,Cheng Hock Toh,Cheng Hock Toh +12 more
TL;DR: A new mechanism for acute lung injury after severe trauma is elucidated and it is proposed that circulating histones are viable therapeutic targets for improving survival outcomes in patients.