Chen Wang
Fudan University
10 Papers
1 Citations
Chen Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Radioresistance & Radiosensitivity. The author has an hindex of 5, co-authored 8 publications.
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Papers
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
TL;DR: It is suggested that exosomes from irradiated lung cancer cells regulated the motility of recipient cells by accelerating glycolytic process, where exosomal ALDOA and ALDH3A1 proteins were important signaling factors.
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Inhibition of Cathepsin D (CTSD) enhances radiosensitivity of glioblastoma cells by attenuating autophagy.
Wang Zheng,Qianping Chen,Chen Wang,Dan Yao,Lin Zhu,Yan Pan,Jianghong Zhang,Yang Bai,Chunlin Shao +8 more
TL;DR: It is revealed for the first time that CTSD regulated the radiosensitivity of glioblastoma by affecting the fusion of autophagosomes and lysosomes, leading to radiosensitization ultimately.
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ANXA6 Contributes to Radioresistance by Promoting Autophagy via Inhibiting the PI3K/AKT/mTOR Signaling Pathway in Nasopharyngeal Carcinoma.
Qianping Chen,Wang Zheng,Lin Zhu,Dan Yao,Chen Wang,Yimeng Song,Songling Hu,Hongxia Liu,Yang Bai,Yan Pan,Jianghong Zhang,Jian Guan,Chunlin Shao +12 more
TL;DR: It is revealed for the first time that ANXA6 could promote autophagy by inhibiting the PI3K/AKT/mTOR pathway and that it thus contributes to radioresistance of NPC.
Effects of Hypoxia and Radiation-Induced Exosomes on Migration of Lung Cancer Cells and Angiogenesis of Umbilical Vein Endothelial Cells.
Fang Mo,Yanwu Xu,Junling Zhang,Lin Zhu,Chen Wang,Xiaofei Chu,Yan Pan,Yang Bai,Chunlin Shao,Jianghong Zhang +9 more
TL;DR: The exosome-derived protein of angiopoietin-like 4 (ANGPTL4) contributed to the migration of A549 cells as well as the angiogenesis of HUVECs, suggesting its potential as an effective diagnostic biomarker of metastasis and even a therapeutic target of lung cancer.
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Inhibition of Cathepsin D (CTSD) enhances radiosensitivity of glioblastoma cells by attenuating autophagy
Wang Zheng,Qianping Chen,Chen Wang,Dan Yao,Lin-lin Zhu,Yan Pan,Jianghong Zhang,Yang Bai,Chunlin Shao +8 more
TL;DR: It is revealed for the first time that CTSD regulated the radiosensitivity of glioblastoma by affecting the fusion of autophagosomes and lysosomes.
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