Céline Verstuyft
University of Paris-Sud
145 Papers
1.1K Citations
Céline Verstuyft is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 35, co-authored 122 publications. Previous affiliations of Céline Verstuyft include Pierre-and-Marie-Curie University & Université Paris-Saclay.
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Papers
Genetic Determinants of Response to Clopidogrel and Cardiovascular Events
Tabassome Simon,Céline Verstuyft,Murielle Mary-Krause,Lina Quteineh,Elodie Drouet,Nicolas Meneveau,P. Gabriel Steg,Jean Ferrières,Nicolas Danchin,Laurent Becquemont,Abstr Act +10 more
TL;DR: Among patients with an acute myocardial infarction who were receiving clopidogrel, those carrying CYP2C19 loss-of-function alleles had a higher rate of subsequent cardiovascular events than those who were not, particularly marked among the patients undergoing percutaneous coronary intervention.
1.8K
Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity
Laurent Bodin,Céline Verstuyft,David-Alexandre Trégouët,Annie Robert,Liliane Dubert,Christian Funck-Brentano,Patrice Jaillon,Philippe Beaune,Pierre Laurent-Puig,Laurent Becquemont,Marie-Anne Loriot +10 more
TL;DR: The simple genotyping of 2 single-nucleotide polymorphisms (SNPs), VKORC1 -1639G>A or 1173C>T and the CYP2C9*3 polymorphisms, could predict a high risk of overdose before initiation of anticoagulation with acenocoumarol, and provide a safer and more individualized antICOagulant therapy.
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Influence of CYP3A5 genetic polymorphism on tacrolimus daily dose requirements and acute rejection in renal graft recipients.
Lina Quteineh,Céline Verstuyft,Valérie Furlan,Antoine Durrbach,Alexia Letierce,Sophie Ferlicot,Anne-Marie Taburet,Bernard Charpentier,Laurent Becquemont +8 more
TL;DR: CYP3A5 genetic polymorphism appeared in this study to affect tacrolimus daily dose requirements and transplantation outcome and Screening for this single nucleotide polymorphism before the transplantation might be helpful for the selection of adequate initial daily dose and to achieve the desired immunosuppression.
119
Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics
Laurent Becquemont,Ana Alfirevic,Ursula Amstutz,Hiltrud Brauch,Evelyne Jacqz-Aigrain,Pierre Laurent-Puig,Miguel Angel Molina,Mikko Niemi,Matthias Schwab,Andrew A. Somogyi,Eric Thervet,Anke-Hilse Maitland-van der Zee,André B.P. van Kuilenburg,Ron H.N. van Schaik,Céline Verstuyft,Mia Wadelius,Ann K. Daly +16 more
TL;DR: Practical recommendations for ten different clinical situations, that have either been approved or not approved by regulatory agencies, and some comments that might accompany the results of these tests, indicating the best drug and doses to be prescribed are proposed.
108
The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes
Stine Thorhauge Zwisler,Stine Thorhauge Zwisler,Thomas P. Enggaard,Thomas P. Enggaard,Lene Noehr-Jensen,Soeren Mikkelsen,Céline Verstuyft,Laurent Becquemont,Soeren H. Sindrup,Kim Brøsen +9 more
TL;DR: There was strong association between less antinociceptive effect of oxycodone and the variant alleles of C3435T and G2677T/A and a moderate association between more severe adverse drug reactions than the carriers of the variant allele of A118G.
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