Candice E. MacDonald
South African Medical Research Council
7 Papers
3 Citations
Candice E. MacDonald is an academic researcher from South African Medical Research Council. The author has contributed to research in topics: Tuberculosis & Medicine. The author has an hindex of 2, co-authored 3 publications.
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Papers
Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa.
Jane A. Shaw,Maynard Meiring,Tracy Cummins,Novel N. Chegou,Conita Claassen,Nelita du Plessis,Marika Flinn,Andriëtte Hiemstra,Léanie Kleynhans,Vinzeigh N. Leukes,Andre G. Loxton,Candice E. MacDonald,Nosipho Mtala,Helmuth Reuter,Donald Simon,Kim Stanley,Gerard Tromp,Wolfgang Preiser,Stephanus T. Malherbe,Gerhard Walzl +19 more
TL;DR: In this paper, the authors assessed the association between antibody positivity and COVID-19 symptom status, medical history, and sociodemographic variables, and found that seropositivity was significantly associated with living in informal housing, residing in a subdistrict with low income per household, and having a low-earning occupation.
GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity.
Stacey Bartlett,Adrian Tandhyka Gemiarto,Minh Dao Ngo,Haressh Sajiir,Semira Hailu,Roma Sinha,Cheng Xiang Foo,Léanie Kleynhans,Happy Tshivhula,Tariq Webber,Helle Bielefeldt-Ohmann,Nicholas P. West,Andriëtte Hiemstra,Candice E. MacDonald,Liv von Voss Christensen,Larry S. Schlesinger,Gerhard Walzl,Mette M. Rosenkilde,Thomas Mandrup-Poulsen,Katharina Ronacher,Katharina Ronacher +20 more
TL;DR: It is found that expression of the oxysterol-receptor GPR183 was reduced in blood from patients with tuberculosis (TB) and type 2 diabetes (T2D) compared to TB patients without T2D and was associated with TB disease severity on chest x-ray.
Optimising the yield from bronchoalveolar lavage on human participants in infectious disease immunology research
Jane A. Shaw,M J Meiring,Devon Allies,L. Cruywagen,Tarryn-Lee Fisher,Kesheera Kasavan,Kelly Roos,Stefan Marc Botha,Candice E. MacDonald,Andriëtte Hiemstra,D. Simon,Ilana C. van Rensburg,Marika Flinn,Ayanda N. Shabangu,Helena Kuivaniemi,Gerard Tromp,Stephanus T. Malherbe,Gerhard Walzl,Nelita du Plessis +18 more
TL;DR: In this paper , the authors investigated the association between the volume of bronchoalveolar lavage (BAL) volume and cell count of 337 participants with active tuberculosis (TB) disease, TB exposure, HIV infection and recent SARS-CoV-2 infection.
Optimising the yield from bronchoalveolar lavage on human participants in infectious disease immunology research
Jane A. Shaw,M J Meiring,Devon Allies,L. Cruywagen,Tarryn-Lee Fisher,Kesheera Kasavan,Kelly Roos,Stefan Marc Botha,Candice E. MacDonald,Andriёtte M. Hiemstra,D. Simon,Ilana C. van Rensburg,Marika Flinn,Ayanda N. Shabangu,Helena Kuivaniemi,Gerard Tromp,Stephanus T. Malherbe,Gerhard Walzl,Nelita du Plessis,Elisa Nemes,Léanie Kleynhans,Shirley McAnda,Charlene Kruger,Tracey Richardson,Firdows Noor,Nosipho Mtala,Robin Storm,A. Chetram,Kim Stanley,David M. Lewinsohn,Deborah A. Lewinsohn,Kevin B. Urdahl,Erwin Schurr,Marianna Orlova,W. Henry Boom,Sarah M. Fortune +35 more
TL;DR: In this article , the authors analyzed the BAL volume yield, and cell yield, concentration, viability, pellet color and differential count for association with important participant characteristics such as active tuberculosis (TB) disease, TB exposure, HIV infection and recent SARS-CoV-2 infection.
Cascade Immune Mechanisms of Protection against Mycobacterium tuberculosis (IMPAc-TB): study protocol for the Household Contact Study in the Western Cape, South Africa
Andriёtte M. Hiemstra,Candice E. MacDonald,Ilana C. van Rensburg,Kim Stanley,Elizna Maasdorp,Shirley Mc Anda,Susanne Tönsing,Jane A. Shaw,Gerard Tromp,Gian D. van der Spuy,Kevin B. Urdahl,David M. Lewinsohn,Helena Kuivaniemi,Nelita du Plessis,Stephanus T. Malherbe,Gerhard Walzl +15 more
TL;DR: In this article , an analytical study exploring protective and non-protective pathways of immunity against Mycobacterium tuberculosis (TB) against adults without HIV infection is performed at community healthcare clinics in high TB incidence areas of the Western Cape Province, South Africa.