Calvin Nguyen
University of California, Los Angeles
5 Papers
Calvin Nguyen is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Wound healing & Biology. The author has an hindex of 4, co-authored 5 publications.
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Papers
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action.
Yan Yan,Qikun Liu,Xin Zang,Xin Zang,Shuguang Yuan,Undramaa Bat-Erdene,Calvin Nguyen,Jianhua Gan,Jiahai Zhou,Jiahai Zhou,Steven E. Jacobsen,Yi Tang +11 more
TL;DR: The discovery and validation of a potent herbicide that targets a critical metabolic enzyme that is required for plant survival is presented and demonstrates the potential of using a resistance-gene-directed approach in the discovery of bioactive natural products.
A quantitative approach to scar analysis.
Hooman Khorasani,Zhong Zheng,Calvin Nguyen,Janette N. Zara,Xinli Zhang,Joyce Wang,Kang Ting,Chia Soo +7 more
TL;DR: It is demonstrated that fractal dimension and lacunarity are more sensitive than Fourier transform analysis for quantification of scar morphology and correlated well with transmission electron microscopy collagen ultrastructure analysis, adding to their validity.
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Delayed wound closure in fibromodulin-deficient mice is associated with increased TGF-β3 signaling.
Zhong Zheng,Calvin Nguyen,Xinli Zhang,Hooman Khorasani,Joyce Wang,Janette N. Zara,Franklin Chu,Wei Yin,Wei Yin,Shen Pang,Anh Le,Kang Ting,Chia Soo +12 more
TL;DR: Increased scarring in fmod(-/-) mice indicates that TGF-β3's antimotility effects predominate over its antifibrotic effects when high TGF -β3 levels disrupt early fibroblastic wound ingress.
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The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
Qikun Liu,Qikun Liu,Sylvain Bischof,Sylvain Bischof,C. Jake Harris,Zhenhui Zhong,Zhenhui Zhong,Lingyu Zhan,Calvin Nguyen,Andrew Q. Rashoff,William D. Barshop,Fei Sun,Suhua Feng,Magdalena E. Potok,Javier Gallego-Bartolomé,Jixian Zhai,James A. Wohlschlegel,Michael Carey,Jeff A. Long,Steven E. Jacobsen +19 more
TL;DR: It is reported that MED12 and MED13 are conditional positive regulators that facilitate the expression of genes depleted in active chromatin marks and the induction of gene expression in response to environmental stimuli in Arabidopsis.
Fibromodulin-Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors during Adult Mouse Skin Wound Healing
Zhong Zheng,Kevin S. Lee,Xinli Zhang,Calvin Nguyen,Ching Yun Hsu,Joyce Z. Wang,Todd Matthew Rackohn,Dwarak Reddy Enjamuri,Maxwell Murphy,Kang Ting,Chia Soo +10 more
TL;DR: This study demonstrates that a single missing gene, FMOD, leads to conspicuous alternations in TGF-β ligand and receptor expression at all stages of wound repair in various cell types, suggesting that FMOD modulates TGF -β bioactivity in a complex way beyond simple physical binding to promote proper wound healing.