Bohua Liu
Academy of Military Medical Sciences
12 Papers
153 Citations
Bohua Liu is an academic researcher from Academy of Military Medical Sciences. The author has contributed to research in topics: Virus & Genome. The author has an hindex of 8, co-authored 12 publications.
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Papers
Immunogenicity and protective efficacy in monkeys of purified inactivated Vero-cell SARS vaccine
E-De Qin,Huiying Shi,Lin Tang,Cui’e Wang,Guohui Chang,Zhifen Ding,Kai Zhao,Jian Wang,Ze Chen,Man Yu,Bingyin Si,Jianyuan Liu,Donglai Wu,Xiaojie Cheng,Baoan Yang,Wenming Peng,Qingwen Meng,Bohua Liu,Weiguo Han,Xunnan Yin,Hongyuan Duan,Da-Wei Zhan,Long Tian,Shuangli Li,Jinsong Wu,Gang Tan,Li Yi,Yu-chuan Li,Yonggang Liu,Hong Liu,Fushuang Lv,Yu Zhang,Xiangang Kong,Baochang Fan,Tao Jiang,Shuli Xu,Xiaomei Wang,Changwen Li,Xiao-hong Wu,Yong-Qiang Deng,Min Zhao,Qingyu Zhu +41 more
TL;DR: The safety of the SARS vaccine was assessed, and whether the antibody dependent enhancement (ADE) occurred under low levels of neutralizing antibody in rhesus was observed, and no side effects were detected.
78
Fatal infection with influenza A (H5N1) virus in China.
TL;DR: To the Editor: A 24-year-old man had pneumonia and respiratory distress in November 2003 and died four days after being hospitalised, and the clinical manifestations were consistent with those of pneumonia.
54
Complete genomic characterization of two tick-borne encephalitis viruses isolated from China
Yu Zhang,Bingyin Si,Bohua Liu,Guo-Hui Chang,Yin-Hui Yang,Qiu-Bo Huo,Yuan-Chun Zheng,Qingyu Zhu +7 more
TL;DR: Phylogenetic trees based on the complete genome, open reading frame and E gene nucleotide sequences all showed that the strains Senzhang and MDJ01 belong to Far-Eastern subtype and cluster with other Chinese TBEV strains, implying that TBEVs prevalent in China were highly conservative.
27
Characterization and application of monoclonal antibodies specific to West Nile virus envelope protein.
June Liu,Bohua Liu,Zhen Cao,Shingo Inoue,Kouichi Morita,Kegong Tian,Qingyu Zhu,George F. Gao +7 more
TL;DR: These monoclonal antibodies specific to WNV envelope (E) protein showed no cross-reactivity with JEV, which suggests that they are useful for further development of highly sensitive, easy handling, and less time-consuming detection kits/tools in WNV surveillance in areas where JEV is epidemic.
14
Virulence of H5N1 virus in mice attenuates after in vitro serial passages
Jing Li,Bohua Liu,Guohui Chang,Yi Hu,Dawei Zhan,Yukun Xia,Yongqiang Li,Yinhui Yang,Qingyu Zhu +8 more
TL;DR: This study indicates that serial passages of VN1194 in vitro lead to adaptation and selection of variants that have markedly decreased virulence and neurotropism, which emphasizes the importance of direct analysis of original or less propagated virus samples.