Bernhard Isaak
University of Bern
9 Papers
40 Citations
Bernhard Isaak is an academic researcher from University of Bern. The author has contributed to research in topics: Brachytherapy & Toxicity. The author has an hindex of 6, co-authored 9 publications.
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Papers
High dose-rate versus low dose-rate brachytherapy for lip cancer.
Pirus Ghadjar,Beat Bojaxhiu,Mathew Simcock,D. Terribilini,Bernhard Isaak,Philipp Gut,Patrick Wolfensberger,J.O. Brömme,Andreas Geretschläger,Frank Behrensmeier,Alessia Pica,Daniel M. Aebersold +11 more
TL;DR: As treatment for lip cancer, HDR and LDR brachytherapy have comparable locoregional control and acute and late toxicity rates and HDR seems to be an effective treatment with acceptable toxicity.
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Association of urethral toxicity with dose exposure in combined high-dose-rate brachytherapy and intensity-modulated radiation therapy in intermediate- and high-risk prostate cancer
Pirus Ghadjar,Oscar Matzinger,Bernhard Isaak,Frank Behrensmeier,Andrea Stroux,Cyrill A. Rentsch,George N. Thalmann,Daniel M. Aebersold +7 more
TL;DR: The urethral V(120) (urethral volume receiving> or =120% of the prescribed HDR-B dose) was associated with acute and late > or = grade 2 GU toxicities and the impact of V( 120) on GU toxicity should be validated in further studies.
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Urethral toxicity vs. cancer control--lessons to be learned from high-dose rate brachytherapy combined with intensity-modulated radiation therapy in intermediate- and high-risk prostate cancer.
Pirus Ghadjar,Cyrill A. Rentsch,Bernhard Isaak,Frank Behrensmeier,George N. Thalmann,Daniel M. Aebersold +5 more
TL;DR: The 3-year BRFS was excellent and late GI toxicity was negligible, however, the late Grade 3 and 4 GU toxicity was unacceptably high, which was associated with a higher number of HDR-B applicators.
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Applicability and dosimetric impact of ultrasound-based preplanning in high-dose-rate brachytherapy of prostate cancer.
Daniel M. Aebersold,Bernhard Isaak,George N. Thalmann,Frank Behrensmeier,Christos Kolotas,Helmut Kranzbühler,R. Mini,Richard H. Greiner +7 more
TL;DR: Preplanning in HDR brachytherapie of the prostate is associated with a substantial decrease of dosimetric implant quality, when the preplan is based on a pretherapeutic ultrasound, and the implant quality is less impaired in subsequent implants of fractionated Brachytherapy.
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Dose calculation for orthovoltage radiotherapy using swiss monte carlo plan
D. Frauchiger,D. Terribilini,Bernhard Isaak,P. Manser,D. Frei,Werner Volken +5 more
- 01 Jan 2007
TL;DR: The goal of the work was to enable the dose calculation of an orthovoltage beam with the Swiss Monte Carlo Plan (SMCP) and it was found that the SMCP was preferred in this situation.
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