Beate Böhm
Goethe University Frankfurt
32 Papers
238 Citations
Beate Böhm is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Psoriatic arthritis & Psoriasis. The author has an hindex of 18, co-authored 30 publications. Previous affiliations of Beate Böhm include University of Erlangen-Nuremberg.
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Papers
Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.
Ulrike Hüffmeier,Steffen Uebe,Arif B. Ekici,John Bowes,Emiliano Giardina,Eleanor Korendowych,Kristina Juneblad,Maria Apel,Ross McManus,Pauline Ho,Ian N. Bruce,Anthony W. Ryan,Frank Behrens,Jesús Lascorz,Jesús Lascorz,Beate Böhm,Heiko Traupe,Jörg Lohmann,Christian Gieger,Heinz-Erich Wichmann,Christine Herold,Michael Steffens,Lars Klareskog,Thomas F. Wienker,Oliver FitzGerald,Gerd-Marie Alenius,Neil McHugh,Neil McHugh,Giuseppe Novelli,Harald Burkhardt,Anne Barton,André Reis +31 more
TL;DR: Functional assays showed reduced binding of this TRAF3IP2 variant to TRAF6, suggesting altered modulation of immunoregulatory signals through altered TRAF interactions as a new and shared pathway for PsA and PsV.
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Genetic Variants of the IL-23R Pathway: Association with Psoriatic Arthritis and Psoriasis Vulgaris, but No Specific Risk Factor for Arthritis
Ulrike Hüffmeier,Jesús Lascorz,Beate Böhm,Jörg Lohmann,Jörg Wendler,Rotraut Mössner,Kristian Reich,Heiko Traupe,Werner Kurrat,Harald Burkhardt,André Reis +10 more
TL;DR: The results indicate that variants of the IL-23R pathway are not specific risk factors for arthritis, but relevant for susceptibility to psoriasis in general.
126
Homeostatic effects of the metalloproteinase disintegrin ADAM15 in degenerative cartilage remodeling
TL;DR: The accelerated development of murine osteoarthritis inADAM15 deficiency as well as the proadhesive and cell survival-promoting in vitro effect of ADAM15 overexpression suggest a homeostatic rather than a destructive role of ADam15 in cartilage remodeling.
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Systematic Linkage Disequilibrium Analysis of SLC12A8 at PSORS5 Confirms a Role in Susceptibility to Psoriasis Vulgaris
Ulrike Hüffmeier,Jesús Lascorz,Heiko Traupe,Beate Böhm,Funda Schürmeier-Horst,Markward Ständer,Reinhard Kelsch,Claudia Baumann,Wolfgang Küster,Harald Burkhardt,André Reis +10 more
TL;DR: It is concluded that SLC12A8 is a susceptibility locus for PsV, and efforts to identify the disease-causing variants are ongoing to establish the exact nature of this association.
59
Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to Susceptibility to Psoriatic Arthritis in German patients
Ulrike Hüffmeier,Xavier Estivill,Eva Riveira-Muñoz,Heiko Traupe,Jörg Wendler,Jörg Lohmann,Beate Böhm,Harald Burkhardt,André Reis +8 more
TL;DR: This is the first non-human leucocyte antigen (HLA) risk factor predisposing only to skin type of psoriasis, supporting the concept of partially overlapping but different aetiological factors underlying skin and joint manifestations.
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