Ayala Lampel
Tel Aviv University
34 Papers
37 Citations
Ayala Lampel is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Chemistry & Peptide. The author has an hindex of 11, co-authored 20 publications. Previous affiliations of Ayala Lampel include City University of New York.
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Papers
Polymeric peptide pigments with sequence-encoded properties
Ayala Lampel,Scott A. McPhee,Hang-Ah Park,Gary G. Scott,Sunita Humagain,Doeke R. Hekstra,Barney Yoo,Pim W. J. M. Frederix,Tai-De Li,Rinat R. Abzalimov,Steven Greenbaum,Tell Tuttle,Chunhua Hu,Christopher J. Bettinger,Rein V. Ulijn +14 more
TL;DR: The use of tyrosine-containing tripeptides as tunable precursors for polymeric pigments and short peptides have low barriers to application and can be easily scaled, suggesting near-term applications in cosmetics and biomedicine.
281
Tunable supramolecular hydrogels for selection of lineage-guiding metabolites in stem cell cultures
Enateri V. Alakpa,Vineetha Jayawarna,Ayala Lampel,Karl Burgess,Christopher C. West,Sanne C.J. Bakker,Sangita Roy,Nadeem Javid,Scott Fleming,Dimitris A. Lamprou,Jingli Yang,Angela Miller,Andrew J. Urquhart,Pim W. J. M. Frederix,Neil T. Hunt,Bruno Péault,Bruno Péault,Rein V. Ulijn,Matthew J. Dalby +18 more
TL;DR: In this article, the authors exploited this phenomenon by combining stem cell differentiation in hydrogels with variable stiffness and metabolomics analysis to identify specific bioactive lipids that are uniquely used up during differentiation.
195
Guiding principles for peptide nanotechnology through directed discovery.
TL;DR: This review explores recent efforts in the directed discovery of functional nanoscale systems and materials based on these same amino acids, but that are not guided by copying or editing biological systems.
Switchable Hydrolase Based on Reversible Formation of Supramolecular Catalytic Site Using a Self-Assembling Peptide
Chunqiu Zhang,Ramim Shafi,Ayala Lampel,Douglas S MacPherson,Charalampos G. Pappas,V. Narang,Tong Wang,Charles Maldarelli,Rein V. Ulijn,Rein V. Ulijn,Rein V. Ulijn +10 more
TL;DR: This work fabricates an artificial hydrolase with pH-switchable activity, achieved by introducing a catalytic histidine residue at the terminus of a pH-responsive peptide which forms a hydrogel which is also catalytically active and maintains its reversible (de-)activation.
130
Formation of functional super-helical assemblies by constrained single heptad repeat
TL;DR: The design of these peptides defines a new direction for assembly of super-helical nanostructures by minimal molecular elements, based on the ability of the non-coded α-aminoisobutyric acid to stabilize very short peptides in helical conformation.