Axel Siefert
Ludwig Maximilian University of Munich
18 Papers
138 Citations
Axel Siefert is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Radiosurgery & Medicine. The author has an hindex of 11, co-authored 17 publications.
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Papers
Microsurgery plus whole brain irradiation versus Gamma Knife surgery alone for treatment of single metastases to the brain: a randomized controlled multicentre phase III trial
Alexander Muacevic,Berndt Wowra,Axel Siefert,Joerg-Christian Tonn,Hans-Jakob Steiger,Friedrich W. Kreth +5 more
TL;DR: In patients harboring a single, small-sized metastasis, Gamma Knife surgery alone is less invasive; local tumor control seems to be as high as after surgery plus whole brain irradiation (WBRT) and distant tumor control is significantly less frequently achieved (after radiosurgery alone).
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Irradiation and Bevacizumab in High-Grade Glioma Retreatment Settings
Maximilian Niyazi,Ute Ganswindt,S.B. Schwarz,Friedrich-Wilhelm Kreth,Jörg-Christian Tonn,Julia Geisler,Christian la Fougère,Lorenz Ertl,Jennifer Linn,Axel Siefert,Claus Belka +10 more
TL;DR: Reirradiation with bevacizumab is a feasible and effective treatment for patients with recurrent high-grade glioma with proven but limited effectiveness and a randomized trial is warranted to finally answer the question whether bevacsuzumab adds substantial benefit to a radiotherapeutic retreatment setting.
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Prognostic factors for survival and radiation necrosis after stereotactic radiosurgery alone or in combination with whole brain radiation therapy for 1–3 cerebral metastases
Lars Schüttrumpf,Maximilian Niyazi,Silke Birgit Nachbichler,Farkhad Manapov,Nathalie Jansen,Axel Siefert,Claus Belka +6 more
TL;DR: SRS alone or in combination with WBRT represents a feasible option as initial treatment for patients with brain metastases; however a significant subset of patients may develop neurological complications.
Photofrin as a radiosensitizer in an in vitro cell survival assay
Ulrike Kulka,Moshe Schaffer,Axel Siefert,P. M. Schaffer,Astrid Ölsner,Kawser Kasseb,Kawser Kasseb,Alfons Hofstetter,Eckhart Dühmke,Giulio Jori,Giulio Jori +10 more
TL;DR: Results of this study showed that Photofrin II can act, under certain conditions as a tumor radiosensitizer, in comparison to irradiation alone.
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Radiologic findings in patients treated with boron neutron capture therapy for glioblastoma multiforme within EORTC trial 11961
Maaike J. Vos,Bernd Turowski,Friedhelm E. Zanella,Philippe Paquis,Axel Siefert,Katalin Hideghéty,Klaus Haselsberger,Frank Grochulla,Tjeerd J. Postma,Andrea Wittig,Jan J. Heimans,Ben J. Slotman,W. Peter Vandertop,Wolfgang Sauerwein +13 more
TL;DR: Although a clear correlation between the BNCT dose and the development of cerebral changes could not be demonstrated, a relationship between the occurrence of these radiologic abnormalities and BN CT seems likely.
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