Axel Kola

TL;DR: This study sequenced the genomes and transcriptomes of 414 drug‐resistant clinical Pseudomonas aeruginosa isolates and identified biomarkers of resistance to four commonly administered antimicrobial drugs, paving the way for the development of a molecular resistance profiling tool that reliably predicts antimicrobial susceptibility based on genomic and transcriptomic markers.

TL;DR: Though the outbreak strain was also disseminated to patients who did not undergo ERCP and environmental sources or medical personnel also contributed to the outbreak, the gut of colonized patients is the main source for CPE, therefore, accurate and stringent reprocessing of endoscopic instruments is extremely important, especially true for more complex instruments involved in the outbreak described here.

TL;DR: A significant reduction in the incidence of VAP is found in patients humidified with HMEs during MV, particularly in patients ventilated for 7 days or longer, although this finding is limited by the exclusion of patients at high risk for airway occlusion from some studies.

TL;DR: It is demonstrated that maternal-neonatal transmission of ESBL-E from mother to child is an important risk factor for colonization of VLBW infants and routine ESbl-E screening of neonates and mothers should be considered as a means of reducing neonatal morbidity and mortality.