Atsushi Ogata
Osaka University
173 Papers
1.2K Citations
Atsushi Ogata is an academic researcher from Osaka University. The author has contributed to research in topics: Tocilizumab & Rheumatoid arthritis. The author has an hindex of 48, co-authored 173 publications. Previous affiliations of Atsushi Ogata include Singapore General Hospital & University of Tsukuba.
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Papers
Flavonoids and Related Compounds as Anti-Allergic Substances
Mari Kawai,Toru Hirano,Shinji Higa,Junsuke Arimitsu,Michiru Maruta,Yusuke Kuwahara,Tomoharu Ohkawara,Keisuke Hagihara,Tomoki Yamadori,Yoshihito Shima,Atsushi Ogata,Ichiro Kawase,Toshio Tanaka +12 more
TL;DR: It is expected that a dietary menu including an appropriate intake of flavonoids may provide a form of complementary and alternative medicine and a preventative strategy for allergic diseases.
348
Transforming growth factor-beta1: differential effects on multiple myeloma versus normal B cells
Mitsuyoshi Urashima,Atsushi Ogata,Dharminder Chauhan,Maria Hatziyanni,María Belén Vidriales,Douglas A. Dedera,Robert L. Schlossman,Kenneth C. Anderson +7 more
TL;DR: It is suggested that TGF-beta1 is produced in MM by both tumor cells and BMSCs, with related tumore cell growth, and that MM cell growth may be enhanced by resistance of tumor cells to the inhibitory effects of TGF -beta1 on normal B-cell proliferation and Ig secretion.
240
Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population
Toshihiro Kishikawa,Yuichi Maeda,Takuro Nii,Daisuke Motooka,Yuki Matsumoto,Masato Matsushita,Hidetoshi Matsuoka,M. Yoshimura,Shoji Kawada,S. Teshigawara,Eri Oguro,Yasutaka Okita,Keisuke Kawamoto,Shinji Higa,Toru Hirano,Masashi Narazaki,Atsushi Ogata,Yukihiko Saeki,Shota Nakamura,Hidenori Inohara,Atsushi Kumanogoh,Kiyoshi Takeda,Yukinori Okada +22 more
TL;DR: A shotgun sequencing-based MWAS highlights a novel link among the gut microbiome, host genome and pathology of RA, which contributes to the understanding of the microbiome’s role in RA aetiology.
196
IL-6 inhibitor for the treatment of rheumatoid arthritis: A comprehensive review
TL;DR: Tocilizumab (TCZ) is an interleukin-6 (IL-6) inhibitor used for the treatment of rheumatoid arthritis (RA) and its effectiveness is supported by evidence from all over the world based on its first decade of use.
194
Myeloma cells express Fas antigen/APO-1 (CD95) but only some are sensitive to anti-Fas antibody resulting in apoptosis
Yoshihito Shima,Norihiro Nishimoto,Atsushi Ogata,Yoshitaka Fujii,Kazuyuki Yoshizaki,Tadamitsu Kishimoto +5 more
TL;DR: The data indicate that only some myeloma cells undergo apoptosis in response to the signal mediated by the Fas antigen, and that effects varied from patient to patient.
135