Antonius E. van Herwaarden
Radboud University Nijmegen
52 Papers
180 Citations
Antonius E. van Herwaarden is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Medicine & Congenital adrenal hyperplasia. The author has an hindex of 16, co-authored 52 publications. Previous affiliations of Antonius E. van Herwaarden include Radboud University Nijmegen Medical Centre.
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Papers
Host and Environmental Factors Influencing Individual Human Cytokine Responses
Rob ter Horst,Martin Jaeger,Sanne P. Smeekens,Marije Oosting,Morris A. Swertz,Yang Li,Vinod Kumar,Dimitri A. Diavatopoulos,Anne F.M. Jansen,Heidi Lemmers,Helga Toenhake-Dijkstra,Antonius E. van Herwaarden,Matthijs Janssen,Renate G. van der Molen,Irma Joosten,Fred C.G.J. Sweep,Johannes W. A. Smit,Romana T. Netea-Maier,Mieke M.J.F. Koenders,Ramnik J. Xavier,Ramnik J. Xavier,Jos W. M. van der Meer,Charles A. Dinarello,Charles A. Dinarello,Norman Pavelka,Norman Pavelka,Cisca Wijmenga,Cisca Wijmenga,Richard A. Notebaart,Leo A. B. Joosten,Mihai G. Netea +30 more
TL;DR: A strong impact of non-genetic host factors (e.g., age and gender) on cytokine production and circulating mediators is shown and annual seasonality is found to be an important environmental factor influencing cytokineproduction.
428
Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits
Raul Aguirre-Gamboa,Irma Joosten,Paulo C. M. Urbano,Renate G. van der Molen,Esther van Rijssen,Bram van Cranenbroek,Marije Oosting,Sanne P. Smeekens,Martin Jaeger,Maria M. Zorro,Sebo Withoff,Antonius E. van Herwaarden,Fred C.G.J. Sweep,Romana T. Netea,Morris A. Swertz,Lude Franke,Ramnik J. Xavier,Leo A. B. Joosten,Mihai G. Netea,Cisca Wijmenga,Cisca Wijmenga,Vinod Kumar,Yang Li,Hans J. P. M. Koenen +23 more
TL;DR: Assessment of the impact of environmental and genetic factors on immune cell populations in peripheral blood from ∼500 healthy volunteers from the Human Functional Genomics Project showed that variations in T cell numbers are more strongly driven by genetic factors, while B cell counts are more environmentally influenced.
200
Testicular Adrenal Rest Tumors: Current Insights on Prevalence, Characteristics, Origin, and Treatment.
Manon Engels,Manon Engels,Paul N. Span,Antonius E. van Herwaarden,Fred C.G.J. Sweep,Nike M. M. L. Stikkelbroeck,Hedi L Claahsen-van der Grinten +6 more
TL;DR: This review provides the reader with current insights on testicular adrenal rest tumors (TARTs), a complication in male patients with congenital adrenal hyperplasia (CAH), and suggests intensified glucocorticoid treatment could improve fertility status in some cases, although studies report contradicting results.
Norepinephrine Dysregulates the Immune Response and Compromises Host Defense during Sepsis
Roeland F. Stolk,Eva van der Pasch,Flavia Naumann,Joost Schouwstra,Steffi Bressers,Antonius E. van Herwaarden,Jelle Gerretsen,Roel Schambergen,Mike Marvin Ruth,Johannes G. van der Hoeven,Henk J. van Leeuwen,Peter Pickkers,Matthijs Kox +12 more
TL;DR: Norepinephrine dysregulates the immune response in mice and humans, and compromises host defense, and may significantly contribute to sepsis-induced immunoparalysis, whereas vasopressin does not have untoward immunologic effects.
113
Association of Maternal Iodine Status With Child IQ: A Meta-Analysis of Individual Participant Data
Deborah Levie,Tim I M Korevaar,Sarah C. Bath,Mario Murcia,Mario Murcia,Mariana Dineva,Sabrina Llop,Sabrina Llop,Mercedes Espada,Mercedes Espada,Antonius E. van Herwaarden,Yolanda B. de Rijke,Jesús Ibarluzea,Jordi Sunyer,Henning Tiemeier,Henning Tiemeier,Margaret P. Rayman,Mònica Guxens,Robin P. Peeters +18 more
TL;DR: Fetal brain development is vulnerable to mild to moderate iodine deficiency, particularly in the first trimester, and potential randomized controlled trials investigating the effect of iodine supplementation in women with mild tomoderate iodine deficiency on child neurodevelopment should begin supplementation not later than the firsttrimester.