Andrew D. Greenhalgh
McGill University
34 Papers
16 Citations
Andrew D. Greenhalgh is an academic researcher from McGill University. The author has contributed to research in topics: Microglia & Inflammation. The author has an hindex of 21, co-authored 31 publications. Previous affiliations of Andrew D. Greenhalgh include Manchester Academic Health Science Centre & University of Bordeaux.
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Papers
Microglia states and nomenclature: A field at its crossroads
Rosa C. Paolicelli,Amanda Sierra,Beth Stevens,Marie-Ève Tremblay,Adriano Aguzzi,Bahareh Ajami,Ido Amit,Etienne Audinat,Ingo Bechmann,Mariko L. Bennett,Frederick Joseph Bennett,Alain Bessis,Knut Biber,Staci D. Bilbo,Mathew Blurton-Jones,Erik Boddeke,Dora Brites,Bert Brône,Guy C. Brown,Oleg Butovsky,Monica J. Carson,Bernardo Castellano,Marco Colonna,Sally A. Cowley,Colm Cunningham,Dimitrios Davalos,Philip L. De Jager,Bart De Strooper,Adam Denes,Bart J. L. Eggen,Ukpong B. Eyo,Elena Galea,Sonia Garel,Florent Ginhoux,Christopher K. Glass,Ozgun Gokce,Diego Gomez-Nicola,Berta González,Siamon Gordon,Manuel B. Graeber,Andrew D. Greenhalgh,Pierre Gressens,Melanie Greter,David H. Gutmann,Christian Haass,Michael T. Heneka,Frank L. Heppner,Soyon Youngae Hong,David Hume,Steffen Jung,Helmut Kettenmann,Jonathan Kipnis,Ryuta Koyama,Greg Lemke,Marina A. Lynch,Ania K. Majewska,Marzia Malcangio,Tarja Malm,Renzo Mancuso,Takahiro Masuda,Michela Matteoli,Barry W. McColl,Veronique E. Miron,Anna V. Molofsky,Michelle Monje,Eva Mracsko,Agnès Nadjar,Jonas J. Neher,Urte Neniskyte,Harald Neumann,Mami Noda,Bo Peng,Francesca Peri,V. Hugh Perry,Phillip G. Popovich,Clare Pridans,Josef Priller,Marco Prinz,Davide Ragozzino,Richard M. Ransohoff,Michael W. Salter,Anne Schaefer,Dorothy A. Schafer,Michal Schwartz,Mikael Simons,Cody Smith,Wolfgang J. Streit,Tuan Leng Tay,Li-Huei Tsai,Alexei Verkhratsky,Rommy von Bernhardi,Hiroaki Wake,Valérie Wittamer,Susanne A. Wolf,Longyan Wu,Tony Wyss-Coray +95 more
TL;DR: A conceptual framework and recommendations on the use of microglial nomenclature for researchers, reviewers, and editors are discussed in this article . But, as mentioned before, the proposed framework does not consider the role of functional microglia in development, plasticity, aging, and diseases.
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TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord.
Antje Kroner,Andrew D. Greenhalgh,Juan G. Zarruk,Rosmarini Passos dos Santos,Matthias Gaestel,Samuel David +5 more
TL;DR: It is shown that TNF prevents phagocytosis-mediated conversion from M1 to M2 cells in vitro and in vivo in spinal cord injury (SCI), and transplantation experiments show that increased loading of M2 macrophages with iron induces a rapid switch from M2 to M1 phenotype.
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Immune cell regulation of glia during CNS injury and disease.
TL;DR: In their Review, Greenhalgh, David and Bennett highlight the importance of interactions between resident and infiltrating immune cells and the brain’s other major cellular population — glial cells — for brain function.
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Differences in the Phagocytic Response of Microglia and Peripheral Macrophages after Spinal Cord Injury and Its Effects on Cell Death
TL;DR: This work suggests that microglia play a major role in the early response to SCI, byphagocytosing damaged and degenerating tissue, processing phagocytic material efficiently, and remaining viable.
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Microglial TNF-α Suppresses Cocaine-Induced Plasticity and Behavioral Sensitization
Gil M. Lewitus,Sarah C. Konefal,Andrew D. Greenhalgh,Horia Pribiag,Keanan Augereau,David Stellwagen +5 more
TL;DR: It is shown that repeated administration of cocaine activates striatal microglia and induces TNF-α production, which in turn depresses glutamatergic synaptic strength in the NAc core and limits the development of behavioral sensitization.
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