Andrew Craig

TL;DR: It is determined whether altered maturation or development of one or more oligodendrocyte lineage stages plays a role in the pathogenesis of the myelination disturbances associated with exposure to chronic hypoxia and whether blockade of A1 adenosine receptor action with theAdenosine antagonist caffeine can prevent hypoxIA‐induced white matter injury.

TL;DR: It is suggested that oligodendroglia and axons are the major source of extracellular glutamate in developing white matter during hypoxia-ischemia, and that astrocytes fail to accumulate the glutamate lost from these sources.

TL;DR: During acute cellular rejection after lung transplantation, there is an intra-allograft oligoclonal expansion of cytotoxic CD8+ T cells, and expanded T cell clones persist as transcriptionally reprogrammed, airway-centric tissue resident memory T cells.

TL;DR: In this paper , a variety of enzymes have been used to perform tissue digestion, each with potential limitations, and a framework for selecting an enzymatic digestion protocol best suited to the scientific question and allow for comparison of studies using different protocols.