Alan W. Stitt
Queen's University Belfast
258 Papers
1.7K Citations
Alan W. Stitt is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Diabetic retinopathy & Medicine. The author has an hindex of 68, co-authored 236 publications. Previous affiliations of Alan W. Stitt include Katholieke Universiteit Leuven & Vision-Sciences, Inc..
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Papers
The progress in understanding and treatment of diabetic retinopathy
Alan W. Stitt,Tim M. Curtis,Mei Chen,Reinhold J. Medina,Gareth J. McKay,Alicia J. Jenkins,Tom A. Gardiner,Timothy J. Lyons,Hans-Peter Hammes,Rafael Simó,Noemi Lois +10 more
TL;DR: It is emphasised that although there have been significant advances, there is still a pressing need for a better understanding basic mechanisms enable development of reliable and robust means to identify patients at highest risk, and to intervene effectively before vision loss occurs.
974
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies
TL;DR: Recent work indicates that diabetes markedly impacts the retinal neurovascular unit and its interdependent vascular, neuronal, glial, and immune cells, leading to identification of new targets and therapeutic strategies that could provide the means to better manage DR.
Neurodegeneration in diabetic retinopathy: does it really matter?
TL;DR: It is concluded that glial, neural and microvascular dysfunction are interdependent and essential for the development of diabetic retinopathy and neuroprotection, itself, can be considered a therapeutic target, independently of its potential impact on microv vascular disease.
The pathology associated with diabetic retinopathy
TL;DR: Based on a strong appreciation of cellular and molecular pathology that underpins diabetic retinopathy, further advances are anticipated as the authors drive towards development of efficacious therapeutic options that can address all stages of disease.
427
Endothelial Progenitors: A Consensus Statement on Nomenclature.
Reinhold J. Medina,Chad L. Barber,Florence Sabatier,Françoise Dignat-George,Juan M. Melero-Martin,Juan M. Melero-Martin,Kiarash Khosrotehrani,Osamu Ohneda,Anna M. Randi,Jerry Kok Yen Chan,Teruhide Yamaguchi,Victor W.M. van Hinsbergh,Mervin C. Yoder,Alan W. Stitt +13 more
TL;DR: This review seeks to discourage the indiscriminate use of “EPCs,” and instead proposes precise terminology based on defining cellular phenotype and function, which should become more precise in the light of strong scientific evidence.
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