Topic
Velvet
About: Velvet is a research topic. Over the lifetime, 287 publications have been published within this topic receiving 2547 citations.
Papers published on a yearly basis
1 / 2
Papers
TL;DR: A comprehensive picture of the molecular interplay between the velvet domain protein family, LaeA and other nuclear regulatory proteins in response to various signal transduction pathway starts to emerge from a jigsaw puzzle of several recent studies.
Abstract: Filamentous fungi produce a number of small bioactive molecules as part of their secondary metabolism ranging from benign antibiotics such as penicillin to threatening mycotoxins such as aflatoxin. Secondary metabolism can be linked to fungal developmental programs in response to various abiotic or biotic external triggers. The velvet family of regulatory proteins plays a key role in coordinating secondary metabolism and differentiation processes such as asexual or sexual sporulation and sclerotia or fruiting body formation. The velvet family shares a protein domain that is present in most parts of the fungal kingdom from chytrids to basidiomycetes. Most of the current knowledge derives from the model Aspergillus nidulans where VeA, the founding member of the protein family, was discovered almost half a century ago. Different members of the velvet protein family interact with each other and the nonvelvet protein LaeA, primarily in the nucleus. LaeA is a methyltransferase-domain protein that functions as a regulator of secondary metabolism and development. A comprehensive picture of the molecular interplay between the velvet domain protein family, LaeA and other nuclear regulatory proteins in response to various signal transduction pathway starts to emerge from a jigsaw puzzle of several recent studies.
528 citations
TL;DR: A review of the recent advance in studying the bioactive components of velvet antlers shows that velvet antler could be used as an important health-promoting tonic with great nutritional and medicinal values.
128 citations
TL;DR: Genome-wide expression analyses revealed that BcVEL1 and BcLAE1 have common and distinct target genes, and both mutants lost the ability to produce OA, to colonize the host tissue, and to form sclerotia.
Abstract: Botrytis cinerea, the gray mold fungus, is an important plant pathogen. Field populations are characterized by variability with regard to morphology, the mode of reproduction (conidiation or sclerotia formation), the spectrum of secondary metabolites (SM), and virulence. Natural variation in bcvel1 encoding the ortholog of Aspergillus nidulans VeA, a member of the VELVET complex, was previously shown to affect light-dependent differentiation, the formation of oxalic acid (OA), and virulence. To gain broader insight into the B. cinerea VELVET complex, an ortholog of A. nidulans LaeA, BcLAE1, a putative interaction partner of BcVEL1, was studied. BcVEL1 but not its truncated versions interacts with BcLAE1 and BcVEL2 (VelB ortholog). In accordance with the expected common as well as specific functions of BcVEL1 and BcLAE1, the deletions of both genes result in similar though not identical phenotypes. Both mutants lost the ability to produce OA, to colonize the host tissue, and to form sclerotia. However, mutants differ with regard to aerial hyphae and conidia formation. Genome-wide expression analyses revealed that BcVEL1 and BcLAE1 have common and distinct target genes. Some of the genes that are underexpressed in both mutants, e.g., those encoding SM-related enzymes, proteases, and carbohydrate-active enzymes, may account for their reduced virulence.
95 citations
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1 Jan 2016
TL;DR: The the velvet glove is universally compatible with any devices to read and is available in the digital library an online access to it is set as public so you can get it instantly.
Abstract: Thank you for reading the velvet glove. Maybe you have knowledge that, people have look numerous times for their chosen novels like this the velvet glove, but end up in infectious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they cope with some malicious virus inside their laptop. the velvet glove is available in our digital library an online access to it is set as public so you can get it instantly. Our book servers hosts in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the the velvet glove is universally compatible with any devices to read.
79 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 57 |
| 2024 | 111 |
| 2023 | 82 |
| 2022 | 111 |
| 2021 | 19 |
| 2020 | 18 |