TL;DR: Anti-inflammatory activity of alcohol and aqueous extract of aerial parts of Uraria lagopoides was determined in the rat paw edema test and showed marked analgesic activity in mice.
Abstract: Anti-inflammatory activity of alcohol and aqueous extract of aerial parts of Uraria lagopoides was determined in the rat paw edema test. At doses of 100 and 200 mg/kg, oral, the extract inhibited edema significantly (p < 0.01) compared with indomethacin (20 mg/kg). It also showed marked analgesic activity in mice (p < 0.01), compared with acetylsalicylic acid (100 mg/kg) in acetic acid-induced writhing test.
TL;DR: Cytotoxicity test suggested that compounds 1–4 possessed slight activity against K-562 and Hela cell lines, with the IC50 values ranging from 26.6 to 56.3 μM.
TL;DR: A new sesquilignan glucoside, urariasinoside A (1), together with eight known compounds, including two lignans, a sesQUiligna, a dilignan, and four flavonoid derivatives were isolated from the aerial parts of Uraria sinensis on the basis of extensive spectroscopic analyses and comparison with literature data.
Abstract: A new sesquilignan glucoside, urariasinoside A (1), together with eight known compounds, including two lignans, a sesquilignan, a dilignan, and four flavonoid derivatives were isolated from the aerial parts of Uraria sinensis. Their structures were determined on the basis of extensive spectroscopic analyses and comparison with literature data. Compound 1 was evaluated for in vitro cytotoxicity activity against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines.
TL;DR: Two potyviruses, uraria mosaic virus (UMV) and passiflora foetida virus Y (PfVY), have been detected in Japan for the first time, from newly bred passionfruit cultivars, suggesting they were distinct from viruses previously isolated from passionfruit.
Abstract: Two potyviruses, uraria mosaic virus (UMV) and passiflora foetida virus Y (PfVY), have been detected in Japan for the first time, from newly bred passionfruit cultivars. Host range analyses and phylogenetic analyses based on full and partial polyprotein coding regions of UMV and PfVY, respectively, suggested they were distinct from viruses previously isolated from passionfruit. Both species belong to the BCMV subgroup within the genus Potyvirus, which contains other pathogenic passionfruit viruses.