Ultraviolet therapy

Abstract: Photoexcited TiO2 particles can drive various chemical reactions due to their strong oxidizing and reducing ability. To investigate the possible use of this effect for cancer treatment, the antitumor activity of photoexcited TiO2 particles was studied in vitro and in vivo. HeLa cells cultured in vitro were completely killed in the presence of TiO2 (50 micrograms/ml) with 10-min UV irradiation by a 500-W-Hg lamp. In contrast, very little cell death was observed from TiO2 treatment without UV irradiation. Photoexcited TiO2 particles also significantly suppressed the growth of HeLa cells implanted in nude mice, compared with those receiving TiO2 alone or UV irradiation alone. The cell death caused by photoexcited TiO2 particles was significantly protected in the presence of L-tryptophan and catalase. These molecules are quenchers of hydroxyl radicals and scavengers of hydrogen peroxide, respectively, suggesting that the cells were killed by the OH. and H2O2 produced from photoexcited TiO2 particles.

Abstract: Evaluation of the Patient: Measurement of Musculoskeletal Function: Electrodiagnosis: Gait Analysis. Diagnosis and Management : Speech and Language Disorders: Psychological Assessment and Management: Psychosocial Diagnosis and Social Services: Vocational Assessment and Management: Prevocation Evaluation: The Epidemiology of Disability as Related to Rehabilitation Medicine: The Neurophysiology of Motor Function: Health Accounting: Functional Assessment of the Long-Term Patient: Diathermy and Superficial Heat, Laser and Cold Therapy: Ultraviolet Therapy: Electrotherapy: Acupuncture in Physiatry: Massage: Therapeutic Exerciseto Maintain Mobility: Therapeutic Exercise to Develop Neuromuscular Coordination: Therapeutic Exercise to Develop Strength and Endurance: Bed Positioning: Transfers: Method, Equipment and Preparation: Wheelchair Prescription: Training for Functional Independence: Training in Homemaking Activities: Upper Extremity Orthotics: Spinal Orthoses: Lower Extremity Orthotics: Prescription Writing in Physical Medicine and Rehabilitation: Rehabilitation of Patients with Complete Stroke: Rehabilitation in Arthritis and Allied Conditions: Traumatic and Congenital Lesions of the Spinal Cord: Aftercare of Fractures: Rehabilitation Management of Diseases of the Motor Unit: Rehabilitation for Swallowing Impairment: Degenerative Diseases of the Central Nervous System: Spine. Disorders and Deformities: Management of Neurogenic Dysfunction of the Bladder and Bowel: Rehabilitation of Children with Brain Damage: Rehabilitation of Respiratory Dysfunction: Rehabilitationof the Patient with Heart Disease: Management of Vascular Disease: Reconstructive Surgery of the Extremities: Diagnosis An

Abstract: The last 2 years has seen a marked increase in the prominence of corneal collagen cross-linking as a treatment strategy for progressive keratoconus. This interest has arisen from a body of laboratory evidence documenting the biomechanical and cellular changes induced by cross-linking. The findings of this research provide a plausible rationale for its use in keratoconus to retard the progression of this common disease. The rapidly growing number of clinical reports suggests, not only a consistent stabilizing effect of cross-linking, but that a variable improvement in corneal shape and visual function may also occur in some patients. However, the marked variation in the clinical course of keratoconus, together with the challenges of accurately evaluating refractive error, visual acuity and even corneal shape in this condition, demands further evidence from randomized controlled clinical trials. The aim of this review is to summarize the theoretical basis and risks of corneal collagen cross-linking, along with the available evidence for its use in keratoconus and other corneal disease states.

Abstract: Background: Only a few clinical trials have been performed on the treatment of generalized vitiligo in children. Recently, narrow-band UVB therapy has been reported to be an effective and safe therapeutic option in adult patients with vitiligo. Objective: We studied the efficacy and safety of UVB (311 nm) therapy in children with generalized vitiligo and evaluated the effect of the therapy on the quality of life in these children. Methods: In an open trial, 51 children (20 males, 31 females) with generalized vitiligo were treated twice weekly with narrow-band UVB radiation therapy for the maximum period of 1 year. The Children's Dermatology Life Quality Index (CDLQI) was used to evaluate the psychosocial impact of disease and treatment and was scored before and after therapy. Results: The treatment resulted in more than 75% overall repigmentation in 53% of patients and in stabilization of the disease in 80%. Responsiveness to therapy was positively correlated with localization of the lesions and the patients' compliance. Adverse events were limited and transient. The better the repigmentation grade, the better the CDLQI scores had improved. Conclusion: Narrow-band UVB therapy is effective and safe in childhood vitiligo; it also may significantly improve the quality of life. (J Am Acad Dermatol 2000;42:245-53.)